Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- V3248 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Beta Catenin Antibody
- Antibody type
- Monoclonal
- Description
- Purified
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 15B8
- Vial size
- 20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)
- Concentration
- 0.2 mg/ml
- Storage
- Store the Beta Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Epithelial to mesenchymal transition-related proteins ZEB1, β-catenin, and β-tubulin-III in idiopathic pulmonary fibrosis.
Monitoring Wnt/β-Catenin Signaling in Skin.
CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth.
A rare case of three different tumors in the same pancreatic specimen: a case report and brief review of the literature.
TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3.
Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development.
Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth.
Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions.
Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the β-Catenin Pathway.
CaMKII represses transcriptionally active β-catenin to mediate acute ethanol neurodegeneration and can phosphorylate β-catenin.
Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis.
Oxygen tension modifies the 'stemness' of human cord blood-derived stem cells.
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome.
Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.
Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells.
Inhibition of mammalian target of rapamycin induces phenotypic reversion in three-dimensional cultures of malignant breast epithelial cells
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development.
Inactivation of Chibby affects function of motile airway cilia.
Chilosi M, Caliò A, Rossi A, Gilioli E, Pedica F, Montagna L, Pedron S, Confalonieri M, Doglioni C, Ziesche R, Grubinger M, Mikulits W, Poletti V
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Jan;30(1):26-38
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Jan;30(1):26-38
Monitoring Wnt/β-Catenin Signaling in Skin.
Ku AT, Miao Q, Nguyen H
Methods in molecular biology (Clifton, N.J.) 2016;1481:127-40
Methods in molecular biology (Clifton, N.J.) 2016;1481:127-40
CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth.
Zhou L, Yang K, Carpenter A, Lang RA, Andl T, Zhang Y
The Biochemical journal 2016 Oct 1;473(19):3291-305
The Biochemical journal 2016 Oct 1;473(19):3291-305
A rare case of three different tumors in the same pancreatic specimen: a case report and brief review of the literature.
De Marchi G, Paiella S, Luchini C, Amodio A, Rusev B, Bassi C, Manfredi R, Frulloni L
Journal of gastrointestinal oncology 2016 Jun;7(3):E52-7
Journal of gastrointestinal oncology 2016 Jun;7(3):E52-7
TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3.
Murphy M, Chatterjee SS, Jain S, Katari M, DasGupta R
Scientific reports 2016 Jun 23;6:28299
Scientific reports 2016 Jun 23;6:28299
Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development.
Zhou L, Yang K, Randall Wickett R, Zhang Y
Cancer medicine 2016 Jul;5(7):1566-79
Cancer medicine 2016 Jul;5(7):1566-79
Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth.
Zhou L, Xu M, Yang Y, Yang K, Wickett RR, Andl T, Millar SE, Zhang Y
PloS one 2016 Jul 29;11(7):e0160425
PloS one 2016 Jul 29;11(7):e0160425
Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions.
Chaudhary A, Bag S, Mandal M, Krishna Karri SP, Barui A, Rajput M, Banerjee P, Sheet D, Chatterjee J
Journal of ethnopharmacology 2015 May 26;166:211-9
Journal of ethnopharmacology 2015 May 26;166:211-9
Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the β-Catenin Pathway.
Wu MH, Lee WJ, Hua KT, Kuo ML, Lin MT
PloS one 2015 Jul 30;10(7):e0134122
PloS one 2015 Jul 30;10(7):e0134122
CaMKII represses transcriptionally active β-catenin to mediate acute ethanol neurodegeneration and can phosphorylate β-catenin.
Flentke GR, Garic A, Hernandez M, Smith SM
Journal of neurochemistry 2014 Feb;128(4):523-35
Journal of neurochemistry 2014 Feb;128(4):523-35
Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis.
Das RK, Anura A, Pal M, Bag S, Majumdar S, Barui A, Chakraborty C, Ray AK, Sengupta S, Paul RR, Chatterjee J
Experimental and molecular pathology 2013 Dec;95(3):259-69
Experimental and molecular pathology 2013 Dec;95(3):259-69
Oxygen tension modifies the 'stemness' of human cord blood-derived stem cells.
Buchheiser A, Houben AP, Bosch J, Marbach J, Liedtke S, Kögler G
Cytotherapy 2012 Sep;14(8):967-82
Cytotherapy 2012 Sep;14(8):967-82
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Raiko L, Siljamäki E, Mahoney MG, Putaala H, Suominen E, Peltonen J, Peltonen S
Experimental dermatology 2012 Aug;21(8):586-91
Experimental dermatology 2012 Aug;21(8):586-91
Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome.
Flentke GR, Garic A, Amberger E, Hernandez M, Smith SM
Birth defects research. Part A, Clinical and molecular teratology 2011 Jul;91(7):591-602
Birth defects research. Part A, Clinical and molecular teratology 2011 Jul;91(7):591-602
Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.
Krause U, Harris S, Green A, Ylostalo J, Zeitouni S, Lee N, Gregory CA
Proceedings of the National Academy of Sciences of the United States of America 2010 Mar 2;107(9):4147-52
Proceedings of the National Academy of Sciences of the United States of America 2010 Mar 2;107(9):4147-52
Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells.
Savage J, Voronova A, Mehta V, Sendi-Mukasa F, Skerjanc IS
Differentiation; research in biological diversity 2010 Jan;79(1):31-40
Differentiation; research in biological diversity 2010 Jan;79(1):31-40
Inhibition of mammalian target of rapamycin induces phenotypic reversion in three-dimensional cultures of malignant breast epithelial cells
Booth R, Kwon S, Monson E
Journal of Biomedical Science and Engineering 2010 ;03(05):476-483
Journal of Biomedical Science and Engineering 2010 ;03(05):476-483
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development.
Chen J, Lan Y, Baek JA, Gao Y, Jiang R
Developmental biology 2009 Oct 1;334(1):174-85
Developmental biology 2009 Oct 1;334(1):174-85
Inactivation of Chibby affects function of motile airway cilia.
Voronina VA, Takemaru K, Treuting P, Love D, Grubb BR, Hajjar AM, Adams A, Li FQ, Moon RT
The Journal of cell biology 2009 Apr 20;185(2):225-33
The Journal of cell biology 2009 Apr 20;185(2):225-33
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of human HeLa cell lysate with Beta Catenin antibody (clone 15B8). Expected molecular weight ~92 kDa.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE human tonsil tissue with Beta Catenin antibody (clone 15B8). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free Beta Catenin Antibody (clone 15B8). Confirmation of Integrity and Purity of the Antibody.