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LearnM00004-1
antibody from Boster Biological Technology
Targeting: CTNNB1
armadillo, beta-catenin, CTNNB
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- M00004-1 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-beta Catenin CTNNB1 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for BETA CATENIN/CTNNB1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat BETA CATENIN/CTNNB1 information: Molecular Weight: 85497 MW; Subcellular Localization: Cytoplasm. Nucleus . Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction. Cell membrane . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Colocalized with RAPGEF2 and TJP1 at cell-cell contacts (By similarity). Cytoplasmic when it is unstabilized (high level of phosphorylation) or bound to CDH1. Translocates to the nucleus when it is stabilized (low level of phosphorylation). Interaction with GLIS2 and MUC1 promotes nuclear translocation. Interaction with EMD inhibits nuclear localization. The majority of beta-catenin is localized to the cell membrane. In interphase, colocalizes with CROCC between CEP250 puncta at the proximal end of centrioles, and this localization is dependent on CROCC and CEP250. In mitosis, when NEK2 activity increases, it localizes to centrosomes at spindle poles independent of CROCC. Colocalizes wi
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- EC-3
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Lithium chloride promotes neural functional recovery after local cerebral ischaemia injury in rats through Wnt signalling pathway activation.
SIRT6 Promotes the Progression of Prostate Cancer via Regulating the Wnt/β-Catenin Signaling Pathway.
Circ-EIF3I facilitates proliferation, migration, and invasion of lung cancer via regulating the activity of Wnt/β-catenin pathway through the miR-1253/NOVA2 axis.
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway.
Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells.
Effect of FH535 on in vitro maturation of porcine oocytes by inhibiting WNT signaling pathway.
Sohlh1 suppresses glioblastoma cell proliferation, migration, and invasion by inhibition of Wnt/β-catenin signaling.
E‑cadherin involvement in human lens epithelial cell transdifferentiation may be associated with N‑cadherin.
Stimulating effect of a newly synthesized sulfonamido-based gallate on articular chondrocytes in vitro.
LiCl inhibits PRRSV infection by enhancing Wnt/β-catenin pathway and suppressing inflammatory responses.
Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β.
Junde Z, Tingting L, Lu Z, Shan C, Dan Y, Yizhen Z
Folia morphologica 2023;82(3):519-532
Folia morphologica 2023;82(3):519-532
SIRT6 Promotes the Progression of Prostate Cancer via Regulating the Wnt/β-Catenin Signaling Pathway.
Zhang X, Chen R, Song LD, Zhu LF, Zhan JF
Journal of oncology 2022;2022:2174758
Journal of oncology 2022;2022:2174758
Circ-EIF3I facilitates proliferation, migration, and invasion of lung cancer via regulating the activity of Wnt/β-catenin pathway through the miR-1253/NOVA2 axis.
Chen T, Feng G, Xing Z, Gao X
Thoracic cancer 2022 Nov;13(22):3133-3144
Thoracic cancer 2022 Nov;13(22):3133-3144
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Bai X, Liu X, Li S, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
Wang Y, Chen Y, Li C, Xiao Z, Yuan H, Zhang Y, Pang D, Tang X, Li M, Ouyang H
Biology 2022 Jan 14;11(1)
Biology 2022 Jan 14;11(1)
Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Sun M, Zhou D, Wu J, Zhou J, Xu J
Marine drugs 2022 Feb 5;20(2)
Marine drugs 2022 Feb 5;20(2)
Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway.
Fu Y, Wang Z, Luo C, Wang Y, Wang Y, Zhong X, Zheng H
Translational oncology 2020 Feb;13(2):423-440
Translational oncology 2020 Feb;13(2):423-440
Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells.
Cong L, Fu S, Zhang J, Zhao J, Zhang Y
Experimental and therapeutic medicine 2018 Jan;15(1):210-216
Experimental and therapeutic medicine 2018 Jan;15(1):210-216
Effect of FH535 on in vitro maturation of porcine oocytes by inhibiting WNT signaling pathway.
Shi M, Cheng J, He Y, Jiang Z, Bodinga BM, Liu B, Chen H, Li Q
Animal science journal = Nihon chikusan Gakkaiho 2018 Apr;89(4):631-639
Animal science journal = Nihon chikusan Gakkaiho 2018 Apr;89(4):631-639
Sohlh1 suppresses glioblastoma cell proliferation, migration, and invasion by inhibition of Wnt/β-catenin signaling.
Liu X, Gao Q, Zhao N, Zhang X, Cui W, Sun J, Fu J, Hao J
Molecular carcinogenesis 2018 Apr;57(4):494-502
Molecular carcinogenesis 2018 Apr;57(4):494-502
E‑cadherin involvement in human lens epithelial cell transdifferentiation may be associated with N‑cadherin.
Huang L, Jiang J, Guo Q, Yang H
Molecular medicine reports 2017 Oct;16(4):5031-5035
Molecular medicine reports 2017 Oct;16(4):5031-5035
Stimulating effect of a newly synthesized sulfonamido-based gallate on articular chondrocytes in vitro.
Lu Z, Wang L, Pan H, Lin X, Lin C, Liu B, Zheng L, Zhao J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(3):1196-209
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(3):1196-209
LiCl inhibits PRRSV infection by enhancing Wnt/β-catenin pathway and suppressing inflammatory responses.
Hao HP, Wen LB, Li JR, Wang Y, Ni B, Wang R, Wang X, Sun MX, Fan HJ, Mao X
Antiviral research 2015 May;117:99-109
Antiviral research 2015 May;117:99-109
Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β.
Fu Y, Zheng Y, Chan KG, Liang A, Hu F
Molecular biology reports 2014 Jun;41(6):3907-13
Molecular biology reports 2014 Jun;41(6):3907-13
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of beta catenin expression in (1) A431 cell lysates; (2)PC-12 cell lysates.
- Additional image
