Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362089 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362089, RRID:AB_10953736
- Product name
- anti-Catenin beta-1 (CTNB1) (pSer45) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr 41, pSer45 (A-T-T (p) -T-A-P-S (p) -L-S) derived from Human b-Catenin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer45
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin.
Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites.
Phosphorylation and regulation of beta-catenin by casein kinase I epsilon.
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.
Provost E, McCabe A, Stern J, Lizardi I, D'Aquila TG, Rimm DL
Oncogene 2005 Apr 14;24(16):2667-76
Oncogene 2005 Apr 14;24(16):2667-76
Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites.
Provost E, Yamamoto Y, Lizardi I, Stern J, D'Aquila TG, Gaynor RB, Rimm DL
The Journal of biological chemistry 2003 Aug 22;278(34):31781-9
The Journal of biological chemistry 2003 Aug 22;278(34):31781-9
Phosphorylation and regulation of beta-catenin by casein kinase I epsilon.
Sakanaka C
Journal of biochemistry 2002 Nov;132(5):697-703
Journal of biochemistry 2002 Nov;132(5):697-703
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.
Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M, Ben-Neriah Y, Alkalay I
Genes & development 2002 May 1;16(9):1066-76
Genes & development 2002 May 1;16(9):1066-76
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.
Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X
Cell 2002 Mar 22;108(6):837-47
Cell 2002 Mar 22;108(6):837-47
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