Antibody data
- Antibody Data
- Antigen structure
- References [90]
- Comments [0]
- Validations [0]
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- Product number
- 66379-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Beta Catenin antibody
- Antibody type
- Monoclonal
- Description
- Beta Catenin antibody (Cat. #66379-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B8A1
- Vial size
- 20ul, 150ul
Submitted references Mechanical strain regulates osteogenesis via Antxr1/LncRNA H19/Wnt/β-catenin axis.
NCAPD2 promotes the malignant progression of oral squamous cell carcinoma via the Wnt/β-catenin pathway.
Effect of high-fat diet on the fatty acid profiles of brain in offspring mice exposed to maternal gestational diabetes mellitus.
PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.
Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice.
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
MiR-92a-2-5p suppresses esophageal squamous cell carcinoma cell proliferation and invasion by targeting PRDX2.
Transcriptomic analysis of rat brain response to alternating current electrical stimulation: unveiling insights via single-nucleus RNA sequencing.
Association of variants in GJA8 with familial acorea-microphthalmia-cataract syndrome.
The Mechanics of Tumor Cells Dictate Malignancy via Cytoskeleton-Mediated APC/Wnt/β-Catenin Signaling.
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties.
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
POFUT1 promotes gastric cancer progression through Notch/Wnt dual signaling pathways dependent on the parafibromin-NICD1-β-catenin complex.
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
The Effect of Adipocyte-Secreted Factors in Activating Focal Adhesion Kinase-Mediated Cell Signaling Pathway towards Metastasis in Breast Cancer Cells.
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Microcystin-LR accelerates follicular atresia in mice via JNK-mediated adherent junction damage of ovarian granulosa cells.
Enhanced binding of β-catenin and β-TrCP mediates LMPt's anti-CSCs activity in colorectal cancer.
Osteocytes Exposed to Titanium Particles Inhibit Osteoblastic Cell Differentiation via Connexin 43.
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering.
IKKα aggravates renal fibrogenesis by positively regulating the Wnt/β-catenin pathway.
SARS-CoV-2 infection of kidney tissues from severe COVID-19 patients.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Lmpt regulates the function of Drosophila muscle by acting as a repressor of Wnt signaling.
CDC20 inhibition alleviates fibrotic response of renal tubular epithelial cells and fibroblasts by regulating nuclear translocation of β-catenin.
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma.
mTOR is involved in LRP5-induced osteogenic differentiation of normal and aged periodontal ligament stem cells in vitro.
Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling.
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Cerebroprotein hydrolysate injection is involved in promoting long-term angiogenesis, vessel diameter and density after cerebral ischemia in mice.
Benzophenone-1 induced aberrant proliferation and metastasis of ovarian cancer cells via activated ERα and Wnt/β-catenin signaling pathways.
Exosomal microRNA-19b targets FBXW7 to promote colorectal cancer stem cell stemness and induce resistance to radiotherapy.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway.
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Effect of Sox18 on the Induction Ability of Dermal Papilla Cells in Hu Sheep.
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Osteoporosis via MicroRNA-27a-Induced Inhibition of DKK2-Mediated Wnt/β-Catenin Pathway.
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Circular RNA circβ-catenin aggravates the malignant phenotype of non-small-cell lung cancer via encoding a peptide.
ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradation.
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Reelin promotes oligodendrocyte precursors migration via the Wnt/β-catenin signaling pathway.
Overexpressed P75CUX1 promotes EMT in glioma infiltration by activating β-catenin.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
The Immp2l Mutation Causes Ovarian Aging Through ROS-Wnt/β-Catenin-Estrogen Pathway: Preventive Effect of Melatonin.
TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple.
Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq.
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wnt5a induces and maintains prostate cancer cells dormancy in bone.
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
Anti-tumor effect of HOTAIR-miR-613-SNAI2 axis through suppressing EMT and drug resistance in laryngeal squamous cell carcinoma.
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.
Liu L, Guo J, Tong X, Zhang M, Chen X, Huang M, Zhu C, Bennett S, Xu J, Zou J
Journal of cellular physiology 2024 May;239(5):e31214
Journal of cellular physiology 2024 May;239(5):e31214
NCAPD2 promotes the malignant progression of oral squamous cell carcinoma via the Wnt/β-catenin pathway.
Ma P, Yu H, Zhu M, Liu L, Cheng L, Han Z, Jin W
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):588-601
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):588-601
Effect of high-fat diet on the fatty acid profiles of brain in offspring mice exposed to maternal gestational diabetes mellitus.
Yu HT, Xu WH, Gong JY, Chen YF, He Y, Chen ST, Wu YY, Liu GL, Zhang HY, Xie L
International journal of obesity (2005) 2024 Jun;48(6):849-858
International journal of obesity (2005) 2024 Jun;48(6):849-858
PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.
Ling X, Liu L, Jiang A, Shi X, Liu L, Wang X, Lu C, Ren C, Yu Z
Molecular and cellular endocrinology 2024 Jan 1;579:112083
Molecular and cellular endocrinology 2024 Jan 1;579:112083
Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice.
Yu HT, Gong JY, Xu WH, Chen YR, Li YT, Chen YF, Liu GL, Zhang HY, Xie L
The Journal of nutrition 2024 Feb;154(2):590-599
The Journal of nutrition 2024 Feb;154(2):590-599
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
He J, Hou L, Liu Q, Zhou R
Biochemical and biophysical research communications 2024 Feb 12;696:149501
Biochemical and biophysical research communications 2024 Feb 12;696:149501
MiR-92a-2-5p suppresses esophageal squamous cell carcinoma cell proliferation and invasion by targeting PRDX2.
Zhan X, Li J, Zeng R, Lei L, Feng A, Yang Z
Experimental cell research 2024 Feb 1;435(1):113925
Experimental cell research 2024 Feb 1;435(1):113925
Transcriptomic analysis of rat brain response to alternating current electrical stimulation: unveiling insights via single-nucleus RNA sequencing.
Wang Y, Ma Y, Zhong Q, Song B, Liu Q
MedComm 2024 Apr;5(4):e514
MedComm 2024 Apr;5(4):e514
Association of variants in GJA8 with familial acorea-microphthalmia-cataract syndrome.
Dong S, Zou T, Zhen F, Wang T, Zhou Y, Wu J, Nagata T, Matsushita I, Gong B, Kondo H, Li Q, Zhang H
European journal of human genetics : EJHG 2024 Apr;32(4):413-420
European journal of human genetics : EJHG 2024 Apr;32(4):413-420
The Mechanics of Tumor Cells Dictate Malignancy via Cytoskeleton-Mediated APC/Wnt/β-Catenin Signaling.
Chen X, Xu Z, Tang K, Hu G, Du P, Wang J, Zhang C, Xin Y, Li K, Zhang Q, Hu J, Zhang Z, Yang M, Wang G, Tan Y
Research (Washington, D.C.) 2023;6:0224
Research (Washington, D.C.) 2023;6:0224
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
Yang Z, Wei J, Wang Y, Du Y, Song S, Li J, Su Z, Shi Y, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties.
Wang S, Hu T, He M, Gu Y, Cao X, Yuan Z, Lv X, Getachew T, Quan K, Sun W
Frontiers in veterinary science 2023;10:1127501
Frontiers in veterinary science 2023;10:1127501
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Xu B, Fang J, Wang J, Jin X, Liu S, Song K, Wang P, Liu J, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Tang Y, Wan F, Tang X, Lin Y, Zhang H, Cao J, Yang R
International immunopharmacology 2023 Sep;122:110584
International immunopharmacology 2023 Sep;122:110584
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Zhou Q, Fang G, Pang Y, Wang X
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
Shang B, Lu F, Jiang S, Xing M, Mao X, Yang G, Zhang H
Aging 2023 Sep 18;15(18):9614-9632
Aging 2023 Sep 18;15(18):9614-9632
POFUT1 promotes gastric cancer progression through Notch/Wnt dual signaling pathways dependent on the parafibromin-NICD1-β-catenin complex.
Dong S, Wang Z, Xiong W
Journal of the Chinese Medical Association : JCMA 2023 Sep 1;86(9):806-817
Journal of the Chinese Medical Association : JCMA 2023 Sep 1;86(9):806-817
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
Yun WJ, Xue H, Yang N, Xiao LJ, Sun HZ, Zheng HC
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):3042-3056
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Su J, Hu S, Ding S, Feng K
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Ma RF, Liu H, Zhao XC, Shan P, Sun P, Xue JJ, Wei G, Zhang H
Bioorganic chemistry 2023 Nov;140:106803
Bioorganic chemistry 2023 Nov;140:106803
The Effect of Adipocyte-Secreted Factors in Activating Focal Adhesion Kinase-Mediated Cell Signaling Pathway towards Metastasis in Breast Cancer Cells.
Mubtasim N, Gollahon L
International journal of molecular sciences 2023 Nov 22;24(23)
International journal of molecular sciences 2023 Nov 22;24(23)
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Ren G, Ma B, Wang J, Xu J, Zhang X, Yin C
Medicine 2023 Nov 17;102(46):e36066
Medicine 2023 Nov 17;102(46):e36066
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Li L, Cao X, Huang L, Huang X, Gu J, Yu X, Zhu Y, Zhou Y, Song Y, Zhu M
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Microcystin-LR accelerates follicular atresia in mice via JNK-mediated adherent junction damage of ovarian granulosa cells.
Du X, Fu Y, Tian Z, Liu H, Xin H, Fu X, Wang F, Zhang H, Zeng X
Ecotoxicology and environmental safety 2023 Mar 1;252:114592
Ecotoxicology and environmental safety 2023 Mar 1;252:114592
Enhanced binding of β-catenin and β-TrCP mediates LMPt's anti-CSCs activity in colorectal cancer.
Wang M, Wang X, Zhao W, Li Y, Cai M, Wang K, Xi X, Zhao C, Zhou H, Shao R, Xia G, Zhang Y, Zhao W
Biochemical pharmacology 2023 Jun;212:115577
Biochemical pharmacology 2023 Jun;212:115577
Osteocytes Exposed to Titanium Particles Inhibit Osteoblastic Cell Differentiation via Connexin 43.
Chai H, Huang Q, Jiao Z, Wang S, Sun C, Geng D, Xu W
International journal of molecular sciences 2023 Jun 29;24(13)
International journal of molecular sciences 2023 Jun 29;24(13)
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Lin H, Ai D, Liu Q, Wang X, Gao J, Chen Q, Ruan L, Tao Y, Gao J, Wang L
Journal of natural products 2023 Jul 28;86(7):1844-1854
Journal of natural products 2023 Jul 28;86(7):1844-1854
Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering.
Liu Z, Huang J, Kang D, Zhou Y, Du L, Qu Q, Wang J, Wen L, Fu D, Hu Z, Miao Y
Acta biomaterialia 2023 Jul 15;165:31-49
Acta biomaterialia 2023 Jul 15;165:31-49
IKKα aggravates renal fibrogenesis by positively regulating the Wnt/β-catenin pathway.
Zhang H, Pan B, Huang W, Ma M, Zhang F, Jiang L, Qian C, Wan X, Cao C
Immunology 2023 Jan;168(1):120-134
Immunology 2023 Jan;168(1):120-134
SARS-CoV-2 infection of kidney tissues from severe COVID-19 patients.
Radovic S, Meng W, Chen L, Paniz Mondolfi AE, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Guo H, Huang Y, Gao SJ
Journal of medical virology 2023 Feb;95(2):e28566
Journal of medical virology 2023 Feb;95(2):e28566
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Gastroenterology 2023 Dec;165(6):1505-1521.e20
CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma.
Jian Y, Zhang L, Gong L, Ding M, Sun X, Yu X, Lv S, Li J, Yang D, Wang S
Cancer cell international 2023 Dec 12;23(1):319
Cancer cell international 2023 Dec 12;23(1):319
Lmpt regulates the function of Drosophila muscle by acting as a repressor of Wnt signaling.
Zhang J, She M, Dai Y, Nie X, Tang M, Zeng Q
Gene 2023 Aug 5;876:147514
Gene 2023 Aug 5;876:147514
CDC20 inhibition alleviates fibrotic response of renal tubular epithelial cells and fibroblasts by regulating nuclear translocation of β-catenin.
He J, Xu S, Jiang M, Wang T, Zhang Y, Jia Z, Bai M, Zhang A
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166663
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166663
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Yang H, Pu L, Li R, Zhu R
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
Journal of gastrointestinal oncology 2023 Apr 29;14(2):900-912
AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.
Wu S, Shen D, Zhao L
Cancer management and research 2022;14:157-167
Cancer management and research 2022;14:157-167
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Cao R, Zhang Z, Tian C, Sheng W, Dong Q, Dong M
Journal of Cancer 2022;13(10):3013-3021
Journal of Cancer 2022;13(10):3013-3021
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
Hu D, Zhang B, Suo Y, Li Z, Wan Z, Zhao W, Chen L, Yin Z, Ning H, Ge Y, Li W
Frontiers in pharmacology 2022;13:779664
Frontiers in pharmacology 2022;13:779664
TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma.
Zhang Y, Yang H, Wang L, Zhou H, Zhang G, Xiao Z, Xue X
Frontiers in oncology 2022;12:918959
Frontiers in oncology 2022;12:918959
mTOR is involved in LRP5-induced osteogenic differentiation of normal and aged periodontal ligament stem cells in vitro.
Yu K, Wang C, Li Y, Jiang Z, Yang G, Wang Y
Journal of molecular histology 2022 Oct;53(5):793-804
Journal of molecular histology 2022 Oct;53(5):793-804
Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
Wang L, Zhao L, Lin Z, Yu D, Jin M, Zhou P, Ren J, Cheng J, Yang K, Wu G, Zhang T, Zhang D
Clinical and translational medicine 2022 May;12(5):e743
Clinical and translational medicine 2022 May;12(5):e743
CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling.
Zhu L, Yang X, Feng J, Mao J, Zhang Q, He M, Mi Y, Mei Y, Jin G, Zhang H
Journal of translational medicine 2022 May 4;20(1):194
Journal of translational medicine 2022 May 4;20(1):194
Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/β-catenin Signaling Pathway.
Song L, Wang X, Qu X, Lv C
Inflammation 2022 Jun;45(3):1118-1132
Inflammation 2022 Jun;45(3):1118-1132
Cerebroprotein hydrolysate injection is involved in promoting long-term angiogenesis, vessel diameter and density after cerebral ischemia in mice.
Myagmar BO, Chen R, Zhang X, Xu R, Jiang W, Cao W, Ji H, Zhang X
Life sciences 2022 Jul 1;300:120568
Life sciences 2022 Jul 1;300:120568
Benzophenone-1 induced aberrant proliferation and metastasis of ovarian cancer cells via activated ERα and Wnt/β-catenin signaling pathways.
Liu X, Zhan T, Gao Y, Cui S, Liu W, Zhang C, Zhuang S
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118370
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118370
Exosomal microRNA-19b targets FBXW7 to promote colorectal cancer stem cell stemness and induce resistance to radiotherapy.
Sun T, Yin YF, Jin HG, Liu HR, Tian WC
The Kaohsiung journal of medical sciences 2022 Feb;38(2):108-119
The Kaohsiung journal of medical sciences 2022 Feb;38(2):108-119
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway.
Fu Y, Gao J, Li Y, Yang X, Zhang Y
International immunopharmacology 2022 Feb;103:108414
International immunopharmacology 2022 Feb;103:108414
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Yu B, Liu L, Cai F, Peng Y, Tang X, Zeng D, Li T, Zhang F, Liang Y, Yuan X, Li J, Dai Z, Liao Q, Lv XB
Cancer cell international 2022 Feb 8;22(1):64
Cancer cell international 2022 Feb 8;22(1):64
Effect of Sox18 on the Induction Ability of Dermal Papilla Cells in Hu Sheep.
Hu T, Lv X, Getachew T, Mwacharo JM, Haile A, Quan K, Li Y, Wang S, Sun W
Biology 2022 Dec 30;12(1)
Biology 2022 Dec 30;12(1)
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Chen Q, Han H, Lin F, Yang L, Feng L, Lai X, Wen Z, Yang M, Wang C, Ma Y, Yin T, Lu G, Lin H, Qi J, Yang Y
Life sciences 2022 Dec 1;310:121077
Life sciences 2022 Dec 1;310:121077
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Sinha T, Ikelle L, Makia MS, Crane R, Zhao X, Kakakhel M, Al-Ubaidi MR, Naash MI
Redox biology 2022 Aug;54:102375
Redox biology 2022 Aug;54:102375
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Chai H, Zhang ZH, Fang JY, She C, Geng C, Xu W
Journal of cellular and molecular medicine 2022 Aug;26(15):4371-4385
Journal of cellular and molecular medicine 2022 Aug;26(15):4371-4385
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L
The EMBO journal 2022 Aug 1;41(15):e110218
The EMBO journal 2022 Aug 1;41(15):e110218
Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Osteoporosis via MicroRNA-27a-Induced Inhibition of DKK2-Mediated Wnt/β-Catenin Pathway.
Wang Y, Zhou X, Wang D
Inflammation 2022 Apr;45(2):780-799
Inflammation 2022 Apr;45(2):780-799
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008
Frontiers in molecular biosciences 2021;8:705008
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6.
Tang J, Gao W, Liu G, Sheng W, Zhou J, Dong Q, Dong M
OncoTargets and therapy 2021;14:2311-2325
OncoTargets and therapy 2021;14:2311-2325
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
Huang D, Yang B, Yao Y, Liao M, Zhang Y, Zeng Y, Zhang F, Wang N, Tong G
Frontiers in pharmacology 2021;12:659325
Frontiers in pharmacology 2021;12:659325
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Circular RNA circβ-catenin aggravates the malignant phenotype of non-small-cell lung cancer via encoding a peptide.
Zhao W, Zhang Y, Zhu Y
Journal of clinical laboratory analysis 2021 Sep;35(9):e23900
Journal of clinical laboratory analysis 2021 Sep;35(9):e23900
ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradation.
Zhang H, Yang X, Zhu L, Li Z, Zuo P, Wang P, Feng J, Mi Y, Zhang C, Xu Y, Jin G, Zhang J, Ye H
FEBS open bio 2021 Oct;11(10):2784-2799
FEBS open bio 2021 Oct;11(10):2784-2799
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
Wu X, Liu L, Zheng Q, Hao H, Ye H, Li P, Yang H
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3553-3566
Acta pharmaceutica Sinica. B 2021 Nov;11(11):3553-3566
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Xu H, Yang Y, Fan L, Deng L, Fan J, Li D, Li H, Zhao RC
Stem cell research & therapy 2021 Mar 12;12(1):176
Stem cell research & therapy 2021 Mar 12;12(1):176
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
Ma Y, Yang X, Han H, Wen Z, Yang M, Zhang Y, Fu J, Wang X, Yin T, Lu G, Qi J, Lin H, Wang X, Yang Y
Bioorganic chemistry 2021 Jun;111:104872
Bioorganic chemistry 2021 Jun;111:104872
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Zhao ZQ, Wu XJ, Cheng YH, Zhou YF, Ma XM, Zhang J, Heng XY, Feng F
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
Reelin promotes oligodendrocyte precursors migration via the Wnt/β-catenin signaling pathway.
Liu Y, Wang Y, Yuan W, Dong F, Zhen F, Liu J, Yang L, Qu X, Yao R
Neurological research 2021 Jul;43(7):543-552
Neurological research 2021 Jul;43(7):543-552
Overexpressed P75CUX1 promotes EMT in glioma infiltration by activating β-catenin.
Xu A, Wang X, Luo J, Zhou M, Yi R, Huang T, Lin J, Wu Z, Xie C, Ding S, Zeng Y, Song Y
Cell death & disease 2021 Feb 4;12(2):157
Cell death & disease 2021 Feb 4;12(2):157
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.
Mou Q, Ji B, Zhao G, Liu Y, Sakurai R, Xie Y, Zhang Q, Dai J, Lu Y, Ge Y, Shi T, Xu S, Rehan VK
Pediatric pulmonology 2021 Aug;56(8):2537-2545
Pediatric pulmonology 2021 Aug;56(8):2537-2545
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
Cheng C, Pei X, Li SW, Yang J, Li C, Tang J, Hu K, Huang G, Min WP, Sang Y
Oncogene 2021 Apr;40(16):2842-2857
Oncogene 2021 Apr;40(16):2842-2857
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Alahdal M, Sun D, Duan L, Ouyang H, Wang M, Xiong J, Wang D
Cancer science 2021 Apr;112(4):1481-1494
Cancer science 2021 Apr;112(4):1481-1494
Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure.
Liu Y, Chen Y, Xie X, Yin A, Yin Y, Liu Y, Dong L, Zhu Z, Zhou J, Zeng Q, Lu X, Chen Z, Wen K, Zuo D
Oxidative medicine and cellular longevity 2020;2020:8096847
Oxidative medicine and cellular longevity 2020;2020:8096847
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Ban Q, Qiao L, Xia H, Xie B, Liu J, Ma Y, Zhang L, Zhang M, Liu LG, Jiao W, Yang S, Li Z, Zheng S, Liu D, Xia J, Qi Z
American journal of translational research 2020;12(8):4757-4771
American journal of translational research 2020;12(8):4757-4771
The Immp2l Mutation Causes Ovarian Aging Through ROS-Wnt/β-Catenin-Estrogen Pathway: Preventive Effect of Melatonin.
He Q, Gu L, Lin Q, Ma Y, Liu C, Pei X, Li PA, Yang Y
Endocrinology 2020 Sep 1;161(9)
Endocrinology 2020 Sep 1;161(9)
TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple.
Zhang R, Li SW, Liu L, Yang J, Huang G, Sang Y
Oncogenesis 2020 May 7;9(5):45
Oncogenesis 2020 May 7;9(5):45
Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq.
Xiang J, Zhang Y, Tuo L, Liu R, Gou D, Liang L, Chen C, Xia J, Tang N, Wang K
Genes & diseases 2020 Mar;7(1):150-159
Genes & diseases 2020 Mar;7(1):150-159
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
Pan S, Wu W, Ren F, Li L, Li Y, Li W, Wang A, Liu D, Dong Y
Life sciences 2020 Mar 1;244:117300
Life sciences 2020 Mar 1;244:117300
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21(CIPI) , cyclin D1 and β-catenin.
Lv L, Zhou M, Zhang J, Liu F, Qi L, Zhang S, Bi Y, Yu Y
FEBS open bio 2020 Jan;10(1):135-146
FEBS open bio 2020 Jan;10(1):135-146
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580
Journal of ethnopharmacology 2020 Apr 24;252:112580
Wnt5a induces and maintains prostate cancer cells dormancy in bone.
Ren D, Dai Y, Yang Q, Zhang X, Guo W, Ye L, Huang S, Chen X, Lai Y, Du H, Lin C, Peng X, Song L
The Journal of experimental medicine 2019 Feb 4;216(2):428-449
The Journal of experimental medicine 2019 Feb 4;216(2):428-449
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Shao TR, Zheng ZN, Chen YC, Wu QQ, Huang GZ, Li F, Zeng WS, Lv XZ
Life sciences 2019 Dec 15;239:117087
Life sciences 2019 Dec 15;239:117087
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, Wang X, Gu C, Wang Y, Ye L, Han L, Lin X, Chen J, Cai J, Li A, Liu S
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
Zhang P, Hua L, Hou H, Du X, He Z, Liu M, Hu X, Yan N
International journal of molecular medicine 2018 Dec;42(6):3344-3354
International journal of molecular medicine 2018 Dec;42(6):3344-3354
Anti-tumor effect of HOTAIR-miR-613-SNAI2 axis through suppressing EMT and drug resistance in laryngeal squamous cell carcinoma.
Zhou JC, Zhang JJ, Ma W, Zhang W, Ke ZY, Ma LG
RSC advances 2018 Aug 20;8(52):29879-29889
RSC advances 2018 Aug 20;8(52):29879-29889
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
Fu N, Zhao SX, Kong LB, Du JH, Ren WG, Han F, Zhang QS, Li WC, Cui P, Wang RQ, Zhang YG, Nan YM
Gene 2017 Jun 30;618:1-7
Gene 2017 Jun 30;618:1-7
E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.
Hong L, Han K, Wu K, Liu R, Huang J, Lunney JK, Zhao S, Yu M
Reproduction (Cambridge, England) 2017 Dec;154(6):765-775
Reproduction (Cambridge, England) 2017 Dec;154(6):765-775
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