600101

antibody from BioLegend
Targeting: CTNNB1 armadillo, beta-catenin, CTNNB
Provider product page for 600101
Western blot
Immunocytochemistry

Antibody data

Product number
600101 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#600101, RRID:AB_315568
Product name
Purified anti-‰-catenin
Antibody type
Polyclonal
Antigen
Recombinant (partial), C-terminal
Description
β-catenin is a 94 kD nuclear and cytoplasmic protein containing Armadillo repeats. This protein is involved in cell-cell adhesion, wingless/WNT signaling pathway, and has been implicated as an oncogene. β-catenin can be modified by glycosylation, phosphorylation, and ubiquitination to target for degradation. This protein has been shown to interact with E-cadherin, α-catenin, axin, APC, GSK-3β, and Tcf/Lef. Dissociation from axin allows cytoplasmic accumulation, after nuclear translocation binds Tcf/Lef. The Poly6001 antibody has been reported to be useful for Western blotting and immunofluorescence of the mouse and human β-catenin protein.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Vial size
50 µl
Storage
Upon receipt, store frozen at -20° C.
CTNNB1 protein structure - 600101 shown in red.