Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10838-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10838-1-AP, RRID:AB_2277491
- Product name
- DNAJB2 antibody
- Antibody type
- Polyclonal
- Description
- DNAJB2 antibody (Cat. #10838-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DNAJB2-related Charcot-Marie-Tooth disease type 2: Pathomechanism insights and phenotypic spectrum widening.
Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle.
A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation.
DNAJB2 expression in normal and diseased human and mouse skeletal muscle.
Saveri P, Magri S, Maderna E, Balistreri F, Lombardi R, Ciano C, Moda F, Garavaglia B, Reale C, Lauria Pinter G, Taroni F, Pareyson D, Pisciotta C
European journal of neurology 2022 Jul;29(7):2056-2065
European journal of neurology 2022 Jul;29(7):2056-2065
Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.
Alalem M, Bhosale M, Ranjan A, Yamamoto S, Kaida A, Nishikawa S, Parrales A, Farooki S, Anant S, Padhye S, Iwakuma T
Cancers 2022 Aug 29;14(17)
Cancers 2022 Aug 29;14(17)
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW, Hong JY, Zhang SX, Jiang LL, Hu HY
Scientific reports 2021 Apr 9;11(1):7815
Scientific reports 2021 Apr 9;11(1):7815
HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle.
Drew BG, Ribas V, Le JA, Henstridge DC, Phun J, Zhou Z, Soleymani T, Daraei P, Sitz D, Vergnes L, Wanagat J, Reue K, Febbraio MA, Hevener AL
Diabetes 2014 May;63(5):1488-505
Diabetes 2014 May;63(5):1488-505
A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation.
Blumen SC, Astord S, Robin V, Vignaud L, Toumi N, Cieslik A, Achiron A, Carasso RL, Gurevich M, Braverman I, Blumen N, Munich A, Barkats M, Viollet L
Annals of neurology 2012 Apr;71(4):509-19
Annals of neurology 2012 Apr;71(4):509-19
DNAJB2 expression in normal and diseased human and mouse skeletal muscle.
Claeys KG, Sozanska M, Martin JJ, Lacene E, Vignaud L, Stockholm D, LaforĂȘt P, Eymard B, Kichler A, Scherman D, Voit T, Israeli D
The American journal of pathology 2010 Jun;176(6):2901-10
The American journal of pathology 2010 Jun;176(6):2901-10
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The DNAJB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DNAJB2. This antibody recognizes human, mouse, rat antigen. The DNAJB2 antibody has been validated for the following applications: ELISA, WB analysis.