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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
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- Product number
- 21875-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- EphA4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EphA4 antibody (Cat. #21875-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation.
Integrative analysis of single-cell embryo data reveals transcriptome signatures for the human pre-implantation inner cell mass.
Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to preserve blood-brain barrier integrity.
Single-chain fragment antibody disrupting the EphA4 function as a therapeutic drug for gastric cancer.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.
A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Monocyte proinflammatory phenotypic control by ephrin type A receptor 4 mediates neural tissue damage.
MiR-145 protected the cell viability of human cerebral cortical neurons after oxygen-glucose deprivation by downregulating EPHA4.
Tong T, Hao C, Shen J, Liu S, Yan S, Aslam MS, Chen Y, Chen W, Li J, Li Y, Zeng J, Li M, You Z, Gulizhaerkezi T, Wei S, Zhu A, Meng X
Brain research bulletin 2024 Jan;206:110838
Brain research bulletin 2024 Jan;206:110838
Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation.
Wang YN, Lee HH, Jiang Z, Chan LC, Hortobagyi GN, Yu D, Hung MC
International journal of biological sciences 2023;19(10):2957-2973
International journal of biological sciences 2023;19(10):2957-2973
Integrative analysis of single-cell embryo data reveals transcriptome signatures for the human pre-implantation inner cell mass.
Wei X, Fang X, Yu X, Li H, Guo Y, Qi Y, Sun C, Han D, Liu X, Li N, Hu H
Developmental biology 2023 Oct;502:39-49
Developmental biology 2023 Oct;502:39-49
Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to preserve blood-brain barrier integrity.
Cash A, de Jager C, Brickler T, Soliman E, Ladner L, Kaloss AM, Zhu Y, Pridham KJ, Mills J, Ju J, Basso EKG, Chen M, Johnson Z, Sotiropoulos Y, Wang X, Xie H, Matson JB, Marvin EA, Theus MH
Proceedings of the National Academy of Sciences of the United States of America 2023 Oct 10;120(41):e2204700120
Proceedings of the National Academy of Sciences of the United States of America 2023 Oct 10;120(41):e2204700120
Single-chain fragment antibody disrupting the EphA4 function as a therapeutic drug for gastric cancer.
Chiang CW, Lin YS, Chang FL, Lin TY, Tsai KC, HuangFu WC, Lee YC
Biochemical and biophysical research communications 2023 Nov 5;680:161-170
Biochemical and biophysical research communications 2023 Nov 5;680:161-170
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.
Loukil A, Ebright E, Uezu A, Gao Y, Soderling SH, Goetz SC
bioRxiv : the preprint server for biology 2023 Dec 21;
bioRxiv : the preprint server for biology 2023 Dec 21;
A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD
Nature cancer 2022 Nov;3(11):1300-1317
Nature cancer 2022 Nov;3(11):1300-1317
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Bhatia S, Nguyen D, Darragh LB, Van Court B, Sharma J, Knitz MW, Piper M, Bukkapatnam S, Gadwa J, Bickett TE, Bhuvane S, Corbo S, Wu B, Lee Y, Fujita M, Joshi M, Heasley LE, Ferris RL, Rodriguez O, Albanese C, Kapoor M, Pasquale EB, Karam SD
Nature communications 2022 Jun 20;13(1):3535
Nature communications 2022 Jun 20;13(1):3535
Monocyte proinflammatory phenotypic control by ephrin type A receptor 4 mediates neural tissue damage.
Kowalski EA, Soliman E, Kelly C, Basso EKG, Leonard J, Pridham KJ, Ju J, Cash A, Hazy A, de Jager C, Kaloss AM, Ding H, Hernandez RD, Coleman G, Wang X, Olsen ML, Pickrell AM, Theus MH
JCI insight 2022 Aug 8;7(15)
JCI insight 2022 Aug 8;7(15)
MiR-145 protected the cell viability of human cerebral cortical neurons after oxygen-glucose deprivation by downregulating EPHA4.
Cai D, Wei D, Chen S, Chen X, Li S, Chen W, He W
Life sciences 2019 Aug 15;231:116517
Life sciences 2019 Aug 15;231:116517
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EPHA4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EPHA4. This antibody recognizes human, mouse antigen. The EPHA4 antibody has been validated for the following applications: ELISA, WB analysis.
