Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11303-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11303-1-AP, RRID:AB_10732939
- Product name
- SERPINE2 antibody
- Antibody type
- Polyclonal
- Description
- SERPINE2 antibody (Cat. #11303-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references BMP6 as a therapeutic target for preeclampsia: enhancing trophoblast invasion and vascular mimicry.
Construction and validation of an osteosarcoma prognostic model reveals that SERPINE2 contributes to the progression and cisplatin sensitivity in osteosarcoma.
KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2.
SerpinE2 promotes M2 polarization in macrophage to accelerate colorectal cancer progression.
Epigenetic modification regulates the ligamentum flavum hypertrophy through miR-335-3p/SERPINE2/β-catenin signaling pathway.
Single-cell RNA sequencing of the carotid artery and femoral artery of rats exposed to hindlimb unloading.
Integrated methylome analysis identifies an epigenetically silenced tumor suppressor RASA4 in small cell lung cancer.
Declining activity of serum response factor in aging aorta in relation to aneurysm progression.
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profiling.
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer.
BAP31 Promotes Tumor Cell Proliferation by Stabilizing SERPINE2 in Hepatocellular Carcinoma.
High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma.
Proteomics analysis of site- and stage-specific protein expression after peripheral nerve injury.
Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding.
Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.
Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects.
Niu Y, Han S, Xiao H, Liu M, Yu Y, Klein C, Lan X, Li Y, Yuan H, Zhang P, Wei D
Cellular and molecular life sciences : CMLS 2026 Jan 23;83(1):79
Cellular and molecular life sciences : CMLS 2026 Jan 23;83(1):79
Construction and validation of an osteosarcoma prognostic model reveals that SERPINE2 contributes to the progression and cisplatin sensitivity in osteosarcoma.
Chen Z, Yu Z, Chang Y, Yang Z, Zhang S, Xie Y, Tang G, Ding G, Lei J, Cai L
International journal of biological macromolecules 2026 Apr;355:151393
International journal of biological macromolecules 2026 Apr;355:151393
KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2.
Liu CC, Li XD
The Kaohsiung journal of medical sciences 2026 Apr 12;:e70211
The Kaohsiung journal of medical sciences 2026 Apr 12;:e70211
SerpinE2 promotes M2 polarization in macrophage to accelerate colorectal cancer progression.
Liu HL, Gao X, Yang W, Li WL
Frontiers in oncology 2025;15:1585935
Frontiers in oncology 2025;15:1585935
Epigenetic modification regulates the ligamentum flavum hypertrophy through miR-335-3p/SERPINE2/β-catenin signaling pathway.
Zhao Y, Jiang S, Chen L, Xiang Q, Lin J, Li W
Cellular & molecular biology letters 2025 Jan 3;30(1):1
Cellular & molecular biology letters 2025 Jan 3;30(1):1
Single-cell RNA sequencing of the carotid artery and femoral artery of rats exposed to hindlimb unloading.
Li C, Pan Y, Wang Y, Li X, Tie Y, Li S, Wang R, Zhao X, Fan J, Yan X, Wang Y, Sun X
Cellular and molecular life sciences : CMLS 2025 Jan 21;82(1):50
Cellular and molecular life sciences : CMLS 2025 Jan 21;82(1):50
Integrated methylome analysis identifies an epigenetically silenced tumor suppressor RASA4 in small cell lung cancer.
Fu M, Zhu Q, Qi J, Zhang X, Wang Z, Wang J, Huang X, Hu Z, Wang W, Hong B, Wang H
Communications biology 2025 Dec 31;9(1):161
Communications biology 2025 Dec 31;9(1):161
Declining activity of serum response factor in aging aorta in relation to aneurysm progression.
Rippe C, Bastrup JA, Holmberg J, Kawka K, Arévalo Martinez M, Albinsson S, Jepps TA, Swärd K
The Journal of biological chemistry 2025 Apr;301(4):108400
The Journal of biological chemistry 2025 Apr;301(4):108400
Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke.
Wang S, Li C, Kang X, Su X, Liu Y, Wang Y, Liu S, Deng X, Huang H, Li T, Lu D, Cai W, Lu Z, Wei L, Lu T
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Dec;44(12):1487-1500
Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profiling.
Zhang D, Sun R, Di C, Li L, Zhao F, Han Y, Zhang W
Computers in biology and medicine 2023 Nov;166:107406
Computers in biology and medicine 2023 Nov;166:107406
Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.
Li T, Su X, Lu P, Kang X, Hu M, Li C, Wang S, Lu D, Shen S, Huang H, Liu Y, Deng X, Cai W, Wei L, Lu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer.
Zhang J, Wu Q, Zhu L, Xie S, Tu L, Yang Y, Wu K, Zhao Y, Wang Y, Xu Y, Chen X, Ma S, Zhang S
Cancer letters 2022 Jan 1;524:268-283
Cancer letters 2022 Jan 1;524:268-283
BAP31 Promotes Tumor Cell Proliferation by Stabilizing SERPINE2 in Hepatocellular Carcinoma.
Zhang X, Jiang D, Yang S, Sun Y, Liu Y, Shi J, Hu C, Pan J, Liu T, Jin B, Yang K
Frontiers in cell and developmental biology 2020;8:607906
Frontiers in cell and developmental biology 2020;8:607906
High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma.
Dokuni R, Nagano T, Jimbo N, Sato H, Kiriu T, Yasuda Y, Yamamoto M, Tachihara M, Kobayashi K, Maniwa Y, Nishimura Y
Respiratory research 2020 Dec 14;21(1):331
Respiratory research 2020 Dec 14;21(1):331
Proteomics analysis of site- and stage-specific protein expression after peripheral nerve injury.
Aiki H, Wada T, Iba K, Oki G, Sohma H, Yamashita T, Kokai Y
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2018 Nov;23(6):1070-1078
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2018 Nov;23(6):1070-1078
Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding.
Stepp MA, Pal-Ghosh S, Tadvalkar G, Li L, Brooks SR, Morasso MI
Scientific reports 2018 Nov 16;8(1):16960
Scientific reports 2018 Nov 16;8(1):16960
Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.
Tang S, Deng S, Guo J, Chen X, Zhang W, Cui Y, Luo Y, Yan Z, He QY, Shen S, Wang T
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):821-833
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):821-833
Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects.
Crispi S, Piccolo MT, D'Avino A, Donizetti A, Viceconte R, Spyrou M, Calogero RA, Baldi A, Signorile PG
Journal of cellular physiology 2013 Sep;228(9):1927-34
Journal of cellular physiology 2013 Sep;228(9):1927-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 11303-1-AP(SERPINE2 antibody) at dilution of 1:100
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 11303-1-AP( SERPINE2 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SERPINE2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SERPINE2. This antibody recognizes human,mouse,rat antigen. The SERPINE2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.