Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17514-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17514-1-AP, RRID:AB_2134726
- Product name
- Cytokeratin 8 antibody
- Antibody type
- Polyclonal
- Description
- Cytokeratin 8 antibody (Cat. #17514-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Immunohistological study of the unexplored vomeronasal organ of an endangered mammal, the dama gazelle (Nanger dama).
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
The IL-33/ST2 Axis Promotes Primary Sjögren's Syndrome by Enhancing Salivary Epithelial Cell Activation and Type 1 Immune Response.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Isolation, culture, and identification of ceruminous gland cells.
Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
KLF4 transactivates TRIM29 expression and modulates keratin network.
Protective effects of miR-155-5p silencing on IFN-γ-induced apoptosis and inflammation in salivary gland epithelial cells.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Cytokeratin expression in epidermal stem cells in skin adnexal tumors.
Wnt5a induces and maintains prostate cancer cells dormancy in bone.
Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators.
Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation.
Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model.
Torres MV, Ortiz-Leal I, Ferreiro A, Rois JL, Sanchez-Quinteiro P
Microscopy research and technique 2023 Sep;86(9):1206-1233
Microscopy research and technique 2023 Sep;86(9):1206-1233
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Qiu Q, Guo G, Guo X, Hu X, Yu T, Liu G, Zhang H, Chen Y, She J
Biomedicines 2023 Mar 13;11(3)
Biomedicines 2023 Mar 13;11(3)
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
Li L, Ling F, Li R, Jiang Y, Long H, Xiao B, Wu J, Long Z, Ma L
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.
Gao S, Chao Y, Li N, Li H, Zhao H, Liu X, Chen W, Dong X
Frontiers in medicine 2022;9:805356
Frontiers in medicine 2022;9:805356
The IL-33/ST2 Axis Promotes Primary Sjögren's Syndrome by Enhancing Salivary Epithelial Cell Activation and Type 1 Immune Response.
Dong Y, Ming B, Gao R, Mo Q, Wu X, Zheng F, Zhong J, Dong L
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2652-2662
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2652-2662
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Isolation, culture, and identification of ceruminous gland cells.
Wang J, He A, Zhu Y, Zhou G, Zhang T
Journal of molecular histology 2022 Apr;53(2):227-237
Journal of molecular histology 2022 Apr;53(2):227-237
Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.
Xie J, Wang Z, Fan W, Liu Y, Liu F, Wan X, Liu M, Wang X, Zeng D, Wang Y, He B, Yan M, Zhang Z, Zhang M, Hou Z, Wang C, Kang Z, Fang W, Zhang L, Lam EW, Guo X, Yan J, Zeng Y, Chen M, Liu Q
Signal transduction and targeted therapy 2021 Sep 4;6(1):333
Signal transduction and targeted therapy 2021 Sep 4;6(1):333
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
KLF4 transactivates TRIM29 expression and modulates keratin network.
Huang R, Fu Y, Deng Y
Biochemistry and biophysics reports 2021 Dec;28:101117
Biochemistry and biophysics reports 2021 Dec;28:101117
Protective effects of miR-155-5p silencing on IFN-γ-induced apoptosis and inflammation in salivary gland epithelial cells.
Zhang J, Zhu L, Shi H, Zheng H
Experimental and therapeutic medicine 2021 Aug;22(2):882
Experimental and therapeutic medicine 2021 Aug;22(2):882
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
Cytokeratin expression in epidermal stem cells in skin adnexal tumors.
Zhou X, Li G, Wang D, Sun X, Li X
Oncology letters 2019 Jan;17(1):927-932
Oncology letters 2019 Jan;17(1):927-932
Wnt5a induces and maintains prostate cancer cells dormancy in bone.
Ren D, Dai Y, Yang Q, Zhang X, Guo W, Ye L, Huang S, Chen X, Lai Y, Du H, Lin C, Peng X, Song L
The Journal of experimental medicine 2019 Feb 4;216(2):428-449
The Journal of experimental medicine 2019 Feb 4;216(2):428-449
Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators.
Wei S, Zou Q, Lai S, Zhang Q, Li L, Yan Q, Zhou X, Zhong H, Lai L
Scientific reports 2016 Jan 19;6:19648
Scientific reports 2016 Jan 19;6:19648
Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation.
Hou R, Wang YW, Liang HF, Zhang ZG, Liu ZM, Zhang BH, Zhang BX, Chen XP
Journal of cancer research and clinical oncology 2015 Nov;141(11):1931-43
Journal of cancer research and clinical oncology 2015 Nov;141(11):1931-43
Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model.
Vijayalingam S, Kuppusamy M, Subramanian T, Strebeck FF, West CL, Varvares M, Chinnadurai G
Cancer gene therapy 2014 Jun;21(6):228-237
Cancer gene therapy 2014 Jun;21(6):228-237
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 17514-1-AP(KRT8 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17514-1-AP(KRT8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cytokeratin 8 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Cytokeratin 8. This antibody recognizes human antigen. The Cytokeratin 8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.