Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Other assay [1]
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Validation data
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- Product number
- V2325 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Cytokeratin 8 + 18 Antibody Cocktail
- Antibody type
- Monoclonal
- Antigen
- A keratin preparation from a human carcinoma (K8.8) and PMC-42 human breast carcinoma cells (DC10) were used as the immunogen for this Cytokeratin 8 + 18 antibody cocktail.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- K8.8 + DC10
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Cytokeratin 8 + 18 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways.
Relationship of CK8/18 expression pattern to breast cancer immunohistochemical subtyping in Egyptian patients.
Concurrent loss of INI1, PBRM1, and BRM expression in epithelioid sarcoma: implications for the cocontributions of multiple SWI/SNF complex members to pathogenesis.
Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract.
Sebaceoma of the external ear canal: an unusual location. Case report and review of the literature.
Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity.
Frohwitter G, Buerger H, VAN Diest PJ, Korsching E, Kleinheinz J, Fillies T
Oncology letters 2016 Jul;12(1):107-113
Oncology letters 2016 Jul;12(1):107-113
Relationship of CK8/18 expression pattern to breast cancer immunohistochemical subtyping in Egyptian patients.
Aiad HA, Samaka RM, Asaad NY, Kandil MA, Shehata MA, Miligy IM
Ecancermedicalscience 2014;8:404
Ecancermedicalscience 2014;8:404
Concurrent loss of INI1, PBRM1, and BRM expression in epithelioid sarcoma: implications for the cocontributions of multiple SWI/SNF complex members to pathogenesis.
Li L, Fan XS, Xia QY, Rao Q, Liu B, Yu B, Shi QL, Lu ZF, Zhou XJ
Human pathology 2014 Nov;45(11):2247-54
Human pathology 2014 Nov;45(11):2247-54
Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract.
Ryan P, Nguyen VH, Gholoum S, Carpineta L, Abish S, Ahmed NN, Laberge JM, Riddell RH
The American journal of surgical pathology 2009 Mar;33(3):475-82
The American journal of surgical pathology 2009 Mar;33(3):475-82
Sebaceoma of the external ear canal: an unusual location. Case report and review of the literature.
El Demellawy D, Escott N, Salama S, Alowami S
Journal of cutaneous pathology 2008 Oct;35(10):963-6
Journal of cutaneous pathology 2008 Oct;35(10):963-6
Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity.
Fillies T, Werkmeister R, Packeisen J, Brandt B, Morin P, Weingart D, Joos U, Buerger H
BMC cancer 2006 Jan 13;6:10
BMC cancer 2006 Jan 13;6:10
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of FFPE human ovarian cancer with Cytokeratin 8 + 18 antibody (K8.8 + DC10).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of FFPE human colon carcinoma with Cytokeratin 8 + 18 antibody (K8.8 + DC10).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free Cytokeratin 8/18 Antibody Cocktail (clones K8.8 + DC10). Confirmation of Integrity and Purity of the Antibody.