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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- ABIN362394 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Keratin 8 (KRT8) (pSer74) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer74 (L-L-S (p) -P-L) derived from Human Keratin 8 (CK8) . Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer74
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18.
Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism.
Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway.
Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic mice.
Nakamichi I, Hatakeyama S, Nakayama KI
Molecular biology of the cell 2002 Oct;13(10):3441-51
Molecular biology of the cell 2002 Oct;13(10):3441-51
Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism.
Prochasson P, Delouis C, Brison O
Nucleic acids research 2002 Aug 1;30(15):3312-22
Nucleic acids research 2002 Aug 1;30(15):3312-22
Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway.
Pankov R, Umezawa A, Maki R, Der CJ, Hauser CA, Oshima RG
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 1;91(3):873-7
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 1;91(3):873-7
Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic mice.
Thorey IS, Ceceña G, Reynolds W, Oshima RG
Molecular and cellular biology 1993 Nov;13(11):6742-51
Molecular and cellular biology 1993 Nov;13(11):6742-51
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