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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [19]
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- Validations
- Immunohistochemistry [1]
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- Product number
- MA5-14425 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Cytokeratin 8 Monoclonal Antibody (TS1), Biotin
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- MA5-14425 targets Cytokeratin 8 in IHC (P) and IP applications and shows reactivity with Human samples.
- Conjugate
- Biotin
- Antibody clone number
- TS1
- Concentration
- 0.2 mg/mL
Submitted references Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease.
Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease.
A novel mechanism of keratin cytoskeleton organization through casein kinase Iα and FAM83H in colorectal cancer.
Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation.
Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.
Aging modulates susceptibility to mouse liver Mallory-Denk body formation.
Identification of nm23-H1 as a metastatic suppressor and prognostic factor in nasopharyngeal carcinoma by proteomic analysis.
Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer.
Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model.
Molecular characterization of breast cancer in young Brazilian women.
Molecular characterization of breast cancer in young Brazilian women.
Characterization of three new serous epithelial ovarian cancer cell lines.
Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss.
Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies.
Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.
Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells.
Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
Fleury H, Communal L, Carmona E, Portelance L, Arcand SL, Rahimi K, Tonin PN, Provencher D, Mes-Masson AM
Genes & cancer 2015 Sep;6(9-10):378-398
Genes & cancer 2015 Sep;6(9-10):378-398
Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease.
Fleury H, Communal L, Carmona E, Portelance L, Arcand SL, Rahimi K, Tonin PN, Provencher D, Mes-Masson AM
Genes & cancer 2015 Sep;6(9-10):378-398
Genes & cancer 2015 Sep;6(9-10):378-398
A novel mechanism of keratin cytoskeleton organization through casein kinase Iα and FAM83H in colorectal cancer.
Kuga T, Kume H, Kawasaki N, Sato M, Adachi J, Shiromizu T, Hoshino I, Nishimori T, Matsubara H, Tomonaga T
Journal of cell science 2013 Oct 15;126(Pt 20):4721-31
Journal of cell science 2013 Oct 15;126(Pt 20):4721-31
Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation.
Snider NT, Leonard JM, Kwan R, Griggs NW, Rui L, Omary MB
The Journal of cell biology 2013 Feb 4;200(3):241-7
The Journal of cell biology 2013 Feb 4;200(3):241-7
Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.
Duan Y, Sun Y, Zhang F, Zhang WK, Wang D, Wang Y, Cao X, Hu W, Xie C, Cuppoletti J, Magin TM, Wang H, Wu Z, Li N, Huang P
The Journal of biological chemistry 2012 Nov 23;287(48):40547-59
The Journal of biological chemistry 2012 Nov 23;287(48):40547-59
Aging modulates susceptibility to mouse liver Mallory-Denk body formation.
Hanada S, Harada M, Abe M, Akiba J, Sakata M, Kwan R, Taniguchi E, Kawaguchi T, Koga H, Nagata E, Ueno T, Sata M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012 Jun;60(6):475-83
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012 Jun;60(6):475-83
Identification of nm23-H1 as a metastatic suppressor and prognostic factor in nasopharyngeal carcinoma by proteomic analysis.
Li X, Hu R, Qu J, He Q, Chen Y, Li J, Ye X, Xiang Y, Yi H
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2012 Jan;37(1):17-26
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2012 Jan;37(1):17-26
Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer.
Létourneau IJ, Quinn MC, Wang LL, Portelance L, Caceres KY, Cyr L, Delvoye N, Meunier L, de Ladurantaye M, Shen Z, Arcand SL, Tonin PN, Provencher DM, Mes-Masson AM
BMC cancer 2012 Aug 29;12:379
BMC cancer 2012 Aug 29;12:379
Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
Snider NT, Weerasinghe SV, Iñiguez-Lluhí JA, Herrmann H, Omary MB
The Journal of biological chemistry 2011 Jan 21;286(3):2273-84
The Journal of biological chemistry 2011 Jan 21;286(3):2273-84
Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model.
Chang HH, Chen BY, Wu CY, Tsao ZJ, Chen YY, Chang CP, Yang CR, Lin DP
Journal of biomedical science 2011 Jan 18;18(1):6
Journal of biomedical science 2011 Jan 18;18(1):6
Molecular characterization of breast cancer in young Brazilian women.
Carvalho LV, Pereira EM, Frappart L, Boniol M, Bernardo WM, Tarricone V, Tavtigian S, Southey MC
Revista da Associacao Medica Brasileira (1992) 2010 May-Jun;56(3):278-87
Revista da Associacao Medica Brasileira (1992) 2010 May-Jun;56(3):278-87
Molecular characterization of breast cancer in young Brazilian women.
Carvalho LV, Pereira EM, Frappart L, Boniol M, Bernardo WM, Tarricone V, Tavtigian S, Southey MC
Revista da Associacao Medica Brasileira (1992) 2010 May-Jun;56(3):278-87
Revista da Associacao Medica Brasileira (1992) 2010 May-Jun;56(3):278-87
Characterization of three new serous epithelial ovarian cancer cell lines.
Ouellet V, Zietarska M, Portelance L, Lafontaine J, Madore J, Puiffe ML, Arcand SL, Shen Z, Hébert J, Tonin PN, Provencher DM, Mes-Masson AM
BMC cancer 2008 May 28;8:152
BMC cancer 2008 May 28;8:152
Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss.
Gilbert S, Ruel A, Loranger A, Marceau N
Apoptosis : an international journal on programmed cell death 2008 Dec;13(12):1479-93
Apoptosis : an international journal on programmed cell death 2008 Dec;13(12):1479-93
Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies.
Tao GZ, Nakamichi I, Ku NO, Wang J, Frolkis M, Gong X, Zhu W, Pytela R, Omary MB
Experimental cell research 2006 Feb 15;312(4):411-22
Experimental cell research 2006 Feb 15;312(4):411-22
Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.
Scott GK, Atsriku C, Kaminker P, Held J, Gibson B, Baldwin MA, Benz CC
Molecular pharmacology 2005 Sep;68(3):606-15
Molecular pharmacology 2005 Sep;68(3):606-15
Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells.
Gilbert S, Loranger A, Marceau N
Molecular and cellular biology 2004 Aug;24(16):7072-81
Molecular and cellular biology 2004 Aug;24(16):7072-81
Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
Sørensen CB, Andresen BS, Jensen UB, Jensen TG, Jensen PK, Gregersen N, Bolund L
Experimental dermatology 2003 Aug;12(4):472-9
Experimental dermatology 2003 Aug;12(4):472-9
Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
Sørensen CB, Andresen BS, Jensen UB, Jensen TG, Jensen PK, Gregersen N, Bolund L
Experimental dermatology 2003 Aug;12(4):472-9
Experimental dermatology 2003 Aug;12(4):472-9
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human breast carcinoma stained with Keratin 8 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.
- Conjugate
- Biotin
