RA0795

antibody from Oursmab

Targeting: TNFSF4 CD252, gp34, OX-40L, TXGP1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0795

Provider

Oursmab

Product name

Oxelumab (Biosimilar Reference Antibody) (TNFSF4)

Antibody type

Monoclonal

Description

Oxelumab (also known as R4930 or huMAb OX40L) is a human monoclonal antibody of the IgG1-kappa isotype that specifically targets OX40 ligand (OX40L, also known as CD252 or TNFSF4), a member of the tumor necrosis factor (TNF) superfamily. By binding to OX40L, oxelumab blocks its interaction with its receptor OX40 (CD134) on activated T cells, thereby inhibiting the co-stimulatory signal that promotes T-cell survival, proliferation, and cytokine production. This mechanism aims to dampen pathogenic T-cell responses in autoimmune and inflammatory conditions.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.