AMAb91262

antibody from Atlas Antibodies

Targeting: ACE2

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AMAb91262

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#AMAb91262, RRID:AB_2665871

Product name

Anti-ACE2

Antibody type

Monoclonal

Description

Monoclonal Antibody against Human ACE2, Clone ID: CL4035, Gene description: angiotensin I converting enzyme 2, Validated applications: WB, IHC, Uniprot ID: Q9BYF1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

CL4035

Vial size

100 µl

Concentration

1.0 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The Apolipoprotein E neutralizing antibody inhibits SARS‐CoV‐2 infection by blocking cellular entry of lipoviral particles

Cui Q, Jeyachandran A, Garcia G, Qin C, Zhou Y, Zhang M, Wang C, Sun G, Liu W, Zhou T, Feng L, Palmer C, Li Z, Aziz A, Gomperts B, Feng P, Arumugaswami V, Shi Y
MedComm 2023;4(5)

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The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus

Dong W, Mead H, Tian L, Park J, Garcia J, Jaramillo S, Barr T, Kollath D, Coyne V, Stone N, Jones A, Zhang J, Li A, Wang L, Milanes-Yearsley M, Torrelles J, Martinez-Sobrido L, Keim P, Barker B, Caligiuri M, Yu J, Gallagher T
Journal of Virology 2022;96(1)

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Protein Expression Profile of ACE2 in the Normal and COVID-19-Affected Human Brain.

Lindskog C, Méar L, Virhammar J, Fällmar D, Kumlien E, Hesselager G, Casar-Borota O, Rostami E
Journal of proteome research 2022 Sep 2;21(9):2137-2145

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Viral S protein histochemistry reveals few potential SARS-CoV-2 entry sites in human ocular tissues

Martin G, Wolf J, Lapp T, Agostini H, Schlunck G, Auw-Hädrich C, Lange C
Scientific Reports 2021;11(1)

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SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule

Werion A, Belkhir L, Perrot M, Schmit G, Aydin S, Chen Z, Penaloza A, De Greef J, Yildiz H, Pothen L, Yombi J, Dewulf J, Scohy A, Gérard L, Wittebole X, Laterre P, Miller S, Devuyst O, Jadoul M, Morelle J, Aboubakar F, Acid S, Amini N, Bailly S, Beauloye C, Castanares-Zapatero D, Coche E, Collienne C, Cornette P, De Brauwer I, Dechamps M, Dupriez F, Froidure A, Garnir Q, Gerber B, Ghaye B, Gilard I, Gohy S, Grégoire C, Hantson P, Jacquet L, Kabamba B, Kautbally S, Lanthier N, Larbaoui F, Liistro G, Maes F, Montiel V, Mwenge B, Pierard S, Pilette C, Pouleur A, Sogorb A, Starkel P, Rodriguez-Villalobos H, Thoma M, Van Caeneghem O, Vancraeynest D
Kidney International 2020;98(5):1296-1307

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Expression of the COVID‐19 receptor ACE2 in the human conjunctiva

Lange C, Wolf J, Auw‐Haedrich C, Schlecht A, Boneva S, Lapp T, Horres R, Agostini H, Martin G, Reinhard T, Schlunck G
Journal of Medical Virology 2020;92(10):2081-2086

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human duodenum and tonsil tissues using AMAb91262 antibody. Corresponding ACE2 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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