Antibody data
- Antibody Data
- Antigen structure
- References [30]
- Comments [0]
- Validations [0]
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- Product number
- 66699-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- ACE2 antibody
- Antibody type
- Monoclonal
- Description
- ACE2 antibody (Cat. #66699-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2F12A4
- Vial size
- 20ul, 150ul
Submitted references Fucoidan from Ascophyllum nodosum and Undaria pinnatifida attenuate SARS-CoV-2 infection in vitro and in vivo by suppressing ACE2 and alleviating inflammation.
Detection of SARS-CoV-2 virus in middle ear effusions and its association with otitis media with effusion.
A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing.
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Determination of soluble angiotensin-converting enzyme 2 in saliva samples and its association with nicotine.
Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication.
Dihydroceramide Δ4-Desaturase 1 Is Not Involved in SARS-CoV-2 Infection.
The dynamic nature of the coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia.
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis.
ACE2 Affects the Expression and Function of IFITM3 During SARS-CoV-2 Pseudovirus Infection in Vero E6 Cells.
Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Differential expression of angiotensin-converting enzyme-2 in human paranasal sinus mucosa in patients with chronic rhinosinusitis.
Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection.
[Congxin Lunzhi Fang improves aortic atherosclerosis and regulates ACE2 expression in ApoE(-/-) mice].
SARS-CoV-2 infection of the oral cavity and saliva.
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells with potential to inhibit SARS-CoV-2 infection and COVID-19 disease progression.
SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue.
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera.
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism.
Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis.
Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells to inhibit SARS-CoV-2 infection and COVID-19 disease progression.
Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera.
Shi FS, Xie YH, Yang YL, Xu LD, Li JJ, Wang X, Zhu LY, Wang WW, Shen PL, Huang YW, Li XQ
Carbohydrate polymers 2024 May 15;332:121884
Carbohydrate polymers 2024 May 15;332:121884
Detection of SARS-CoV-2 virus in middle ear effusions and its association with otitis media with effusion.
Fu X, Wang Z, Chen B, Sun H, Lyu J, Shao J, Lu X, Xu J, Yang J, Chi F, Huang Y, Ren D
Journal of medical virology 2024 Mar;96(3):e29545
Journal of medical virology 2024 Mar;96(3):e29545
A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing.
Dash S, Farnós O, Yang Z, Sudalaiyadum Perumal A, Chaves Fulber JP, Venereo-Sánchez A, Leclerc D, Kamen AA
Protein expression and purification 2023 Oct;210:106295
Protein expression and purification 2023 Oct;210:106295
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Miao L, Yan C, Chen Y, Zhou W, Zhou X, Qiao Q, Xu Z
Cell chemical biology 2023 Mar 16;30(3):248-260.e4
Cell chemical biology 2023 Mar 16;30(3):248-260.e4
Determination of soluble angiotensin-converting enzyme 2 in saliva samples and its association with nicotine.
Bru S, González-Marrón A, Lidón-Moyano C, Carballar R, Martínez-Láinez JM, Pérez-Martín H, Fu M, Pérez-Ortuño R, Ballbè M, Pascual JA, Fernández E, Clotet J, Martínez-Sánchez JM
Environmental research 2023 Jan 1;216(Pt 1):114443
Environmental research 2023 Jan 1;216(Pt 1):114443
Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR
EMBO reports 2023 Dec 6;24(12):e57224
EMBO reports 2023 Dec 6;24(12):e57224
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication.
Montezano AC, Camargo LL, Mary S, Neves KB, Rios FJ, Stein R, Lopes RA, Beattie W, Thomson J, Herder V, Szemiel AM, McFarlane S, Palmarini M, Touyz RM
Scientific reports 2023 Aug 28;13(1):14086
Scientific reports 2023 Aug 28;13(1):14086
Dihydroceramide Δ4-Desaturase 1 Is Not Involved in SARS-CoV-2 Infection.
Hayashi Y, Matsuda K, Tanigawa K, Tanikawa T, Maeda K, Tsuchiya K
Biological & pharmaceutical bulletin 2022;45(10):1559-1563
Biological & pharmaceutical bulletin 2022;45(10):1559-1563
The dynamic nature of the coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia.
Manna VJ, Choi H, Rotoli SM, Caradonna SJ
BBA advances 2022;2:100044
BBA advances 2022;2:100044
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Wang Y, Liu S, Li L, Li L, Zhou X, Wan M, Lou P, Zhao M, Lv K, Yuan Y, Chen Y, Lu Y, Cheng J, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis.
Kawasumi T, Takeno S, Ishino T, Ueda T, Hamamoto T, Takemoto K, Horibe Y, Takashi O
American journal of rhinology & allergy 2022 May;36(3):313-322
American journal of rhinology & allergy 2022 May;36(3):313-322
ACE2 Affects the Expression and Function of IFITM3 During SARS-CoV-2 Pseudovirus Infection in Vero E6 Cells.
Long S, Li S, Zhang X, Peng Q, Chen S, Wang J
Viral immunology 2022 Dec;35(10):653-662
Viral immunology 2022 Dec;35(10):653-662
Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR
bioRxiv : the preprint server for biology 2022 Dec 22;
bioRxiv : the preprint server for biology 2022 Dec 22;
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2.
Tanikawa T, Kiba Y, Yu J, Hsu K, Chen S, Ishii A, Yokogawa T, Suzuki R, Inoue Y, Kitamura M
Molecules (Basel, Switzerland) 2022 Aug 24;27(17)
Molecules (Basel, Switzerland) 2022 Aug 24;27(17)
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
Differential expression of angiotensin-converting enzyme-2 in human paranasal sinus mucosa in patients with chronic rhinosinusitis.
Kawasumi T, Takeno S, Nishimura M, Ishino T, Ueda T, Hamamoto T, Takemoto K, Horibe Y
The Journal of laryngology and otology 2021 Sep;135(9):773-778
The Journal of laryngology and otology 2021 Sep;135(9):773-778
Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection.
Ren H, Ma C, Peng H, Zhang B, Zhou L, Su Y, Gao X, Huang H
Biology direct 2021 Oct 21;16(1):20
Biology direct 2021 Oct 21;16(1):20
[Congxin Lunzhi Fang improves aortic atherosclerosis and regulates ACE2 expression in ApoE(-/-) mice].
Gu Y, Jiang J, Zhang Y, Chen Y, Chen Y, Jiang W, Huang Z, Zhou F
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 Nov 20;41(11):1623-1630
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2021 Nov 20;41(11):1623-1630
SARS-CoV-2 infection of the oral cavity and saliva.
Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Conde CD, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado JO, Lafont BA, Jang SI, Nasir N, Padilla RJ, Murrah VA, Maile R, Lovell W, Wallet SM, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann RH, Cannon G, Anderson CW, Lee RE, Marchesan JT, Bush M, Freire M, Kimple AJ, Herr DL, Rabin J, Grazioli A, Das S, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt SM, Burbelo PD, Chertow D, NIH COVID-19 Autopsy Consortium, HCA Oral and Craniofacial Biological Network, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KM
Nature medicine 2021 May;27(5):892-903
Nature medicine 2021 May;27(5):892-903
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR
PLoS pathogens 2021 Jun;17(6):e1009662
PLoS pathogens 2021 Jun;17(6):e1009662
Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells with potential to inhibit SARS-CoV-2 infection and COVID-19 disease progression.
Sheehan SA, Hamilton KL, Retzbach EP, Balachandran P, Krishnan H, Leone P, Lopez-Gonzalez M, Suryavanshi S, Kumar P, Russo R, Goldberg GS
Experimental cell research 2021 Jun 1;403(1):112594
Experimental cell research 2021 Jun 1;403(1):112594
SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue.
Li S, Li D, Fang J, Liu Q, Cao W, Sun X, Xu G
The ocular surface 2021 Jan;19:249-251
The ocular surface 2021 Jan;19:249-251
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera.
Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MNA, Schilke RM, Woolard MD, Zhang H, COVIDAR Argentina Consortium, Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B
mBio 2021 Feb 16;12(1)
mBio 2021 Feb 16;12(1)
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW
EBioMedicine 2021 Dec;74:103712
EBioMedicine 2021 Dec;74:103712
N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism.
Hayashi Y, Tsuchiya K, Yamamoto M, Nemoto-Sasaki Y, Tanigawa K, Hama K, Ueda Y, Tanikawa T, Gohda J, Maeda K, Inoue JI, Yamashita A
Journal of virology 2021 Aug 10;95(17):e0080721
Journal of virology 2021 Aug 10;95(17):e0080721
Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis.
Huang N, Perez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Domínguez Conde C, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado J, LaFont B, Padilla R, Murrah V, Maile R, Lovell W, Wallet S, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann R, Cannon G, Anderson C, Marchesan J, Bush M, Freire M, Kimple A, Herr DL, Rabin J, Grazioli A, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt S, Burbelo PD, Chertow D, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KM
medRxiv : the preprint server for health sciences 2020 Oct 27;
medRxiv : the preprint server for health sciences 2020 Oct 27;
Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells to inhibit SARS-CoV-2 infection and COVID-19 disease progression.
Sheehan SA, Hamilton KL, Retzbach EP, Balachandran P, Krishnan H, Leone P, Goldberg GS
Research square 2020 Oct 23;
Research square 2020 Oct 23;
Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C, Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM, Cullen PJ, Yamauchi Y
Science (New York, N.Y.) 2020 Nov 13;370(6518):861-865
Science (New York, N.Y.) 2020 Nov 13;370(6518):861-865
Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F
Cell stem cell 2020 Dec 3;27(6):876-889.e12
Cell stem cell 2020 Dec 3;27(6):876-889.e12
Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera.
Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MNA, Schilke RM, Woolard MD, Zhang H, COVIDAR Argentina Consortium, Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B
medRxiv : the preprint server for health sciences 2020 Aug 27;
medRxiv : the preprint server for health sciences 2020 Aug 27;
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