25900-1-AP

antibody from Proteintech Group

Targeting: ADAM10 CD156C, HsT18717, kuz, MADM

Provider product page for 25900-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
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Product number: 25900-1-AP - Provider product page
Provider: Proteintech Group
Product name: ADAM10 antibody
Antibody type: Polyclonal
Description: ADAM10 antibody (Cat. #25900-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ADAM10 protein structure - 25900-1-AP shown in red.

Submitted references ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection.

Bazzone LE, Zhu J, King M, Liu G, Guo Z, MacKay CR, Kyawe PP, Qaisar N, Rojas-Quintero J, Owen CA, Brass AL, McDougall W, Baer CE, Cashman T, Trivedi CM, Gack MU, Finberg RW, Kurt-Jones EA
Nature communications 2024 May 16;15(1):4153

Linarin Ameliorates Restenosis After Vascular Injury in Type 2 Diabetes Mellitus via Regulating ADAM10-Mediated Notch Signaling Pathway.

Jiang A, Liu L, Wang J, Liu Y, Deng S, Jiang T
Cardiovascular toxicology 2024 Jun;24(6):587-597

Nicotinic acetylcholine receptor activation induces BACE1 transcription via the phosphorylation and stabilization of nuclear SP1.

Nakano M, Tsuchida T, Mitsuishi Y, Nishimura M
Neuroscience research 2024 Jun;203:28-41

Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells.

Li XY, Zhou GF, Xie XY, Pu YL, -Chen X, Li CL, Yang J, Wang L, Chen GJ
Molecular biology reports 2024 Apr 5;51(1):484

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43.

Tanaka Y, Ito SI, Honma Y, Hasegawa M, Kametani F, Suzuki G, Kozuma L, Takeya K, Eto M
The Journal of biological chemistry 2023 Nov;299(11):105272

Amyloid futures in the expanding pathology of brain aging and dementia.

Thorwald MA, Silva J, Head E, Finch CE
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Jun;19(6):2605-2617

Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.

Shu X, Wei C, Tu WY, Zhong K, Qi S, Wang A, Bai L, Zhang SX, Luo B, Xu ZZ, Zhang K, Shen C
Cell reports 2023 Feb 28;42(2):112133

Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL-6 trans-signalling.

Huo Y, Yang J, Zheng J, Xu D, Yang M, Tao L, Yao H, Fu X, Yang J, Liu D, Hua R, Zhang J, Sun Y, Hu L, Liu W
Cell proliferation 2022 May;55(5):e13237

IDO1 can impair NK cells function against non-small cell lung cancer by downregulation of NKG2D Ligand via ADAM10.

Fang X, Guo L, Xing Z, Shi L, Liang H, Li A, Kuang C, Tao B, Yang Q
Pharmacological research 2022 Mar;177:106132

NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.

Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763

Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.

Qian X, Zhang S, Duan L, Yang F, Zhang K, Yan F, Ge S
Journal of Alzheimer's disease : JAD 2021;79(4):1785-1800

ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.

Zhang X, Tang L, Zhang Z
Biochemical and biophysical research communications 2021 Jan 22;537:15-21

Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment.

Halakos EG, Connell AJ, Glazewski L, Wei S, Mason RW
Journal of proteomics 2021 Feb 10;232:104068

Epigenetic Regulation of a Disintegrin and Metalloproteinase (ADAM) Transcription in Colorectal Cancer Cells: Involvement of β-Catenin, BRG1, and KDM4.

Sun L, Chen B, Wu J, Jiang C, Fan Z, Feng Y, Xu Y
Frontiers in cell and developmental biology 2020;8:581692

MiR-891a-5p as a prognostic marker and therapeutic target for hormone receptor-positive breast cancer.

Zhang Z, Xu L, He L, Wang J, Shi X, Li Z, Shi S, Hou K, Teng Y, Qu X
Journal of Cancer 2020;11(13):3771-3782

Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway.

Zhang X, Wang J, Gong G, Ma R, Xu F, Yan T, Wu B, Jia Y
Biomolecules & therapeutics 2020 May 1;28(3):259-266

The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.

Hicks DA, Jones AC, Pickering-Brown SM, Hooper NM
Bioscience reports 2020 Apr 30;40(4)

Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.

Li F, Zhang Y, Lu X, Shi J, Gong Q
Life sciences 2019 Oct 1;234:116739

Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.

Zhang Y, Xie JZ, Xu XY, Hu J, Xu T, Jin S, Yang SJ, Wang JZ
Neuroscience bulletin 2019 Aug;35(4):724-734

Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122.

Chai FN, Ma WY, Zhang J, Xu HS, Li YF, Zhou QD, Li XG, Ye XL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1002-1011

Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.

Wu B, Cui J, Yang XM, Liu ZY, Song F, Li L, Jiang JL, Chen ZN
Cell death & disease 2017 Jul 13;8(7):e2925

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