MAB1427

antibody from R&D Systems

Targeting: ADAM10 CD156C, HsT18717, kuz, MADM

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

MAB1427

Provider

R&D Systems

Product name

Anti-Human ADAM10 Ectodomain Monoclonal Antibody (Clone 163003)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human ADAM10, Thr214-Glu672

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

O14672


Isotype

IgG

Vial size

500 µg

References

Submitted references

Non-cell-autonomous function of DR6 in Schwann cell proliferation.

Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF
The EMBO journal 2018 Apr 3;37(7)

---

Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17.

Buchanan PC, Boylan KLM, Walcheck B, Heinze R, Geller MA, Argenta PA, Skubitz APN
The Journal of biological chemistry 2017 Apr 14;292(15):6339-6351

---

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

Zingoni A, Cecere F, Vulpis E, Fionda C, Molfetta R, Soriani A, Petrucci MT, Ricciardi MR, Fuerst D, Amendola MG, Mytilineos J, Cerboni C, Paolini R, Cippitelli M, Santoni A
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 15;195(2):736-48

---

A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).

Breshears LM, Schlievert PM, Peterson ML
The Journal of biological chemistry 2012 Sep 21;287(39):32578-87

---

Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.

Koenen RR, Pruessmeyer J, Soehnlein O, Fraemohs L, Zernecke A, Schwarz N, Reiss K, Sarabi A, Lindbom L, Hackeng TM, Weber C, Ludwig A
Blood 2009 May 7;113(19):4799-809

---

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.

Janes PW, Saha N, Barton WA, Kolev MV, Wimmer-Kleikamp SH, Nievergall E, Blobel CP, Himanen JP, Lackmann M, Nikolov DB
Cell 2005 Oct 21;123(2):291-304

---

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.

Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF
American journal of respiratory cell and molecular biology 2004 Oct;31(4):413-22