Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
Reference
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- Product number
- 10841-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10841-1-AP, RRID:AB_2196506
- Product name
- Syntaxin 6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Syntaxin 6 antibody (Cat. #10841-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer.
Mast cell-mediated inflammation relies on insulin-regulated aminopeptidase controlling cytokine export from the Golgi.
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis.
IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells.
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.
MARCH9-mediated ubiquitination regulates MHC I export from the TGN.
IRAP(+) endosomes restrict TLR9 activation and signaling.
Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.
Poster Session Abstracts.
Pediatric pulmonology 2015 Oct;50 Suppl 41:S193-453
Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation.
HID-1 is a peripheral membrane protein primarily associated with the medial- and trans- Golgi apparatus.
IRAP identifies an endosomal compartment required for MHC class I cross-presentation.
Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X
Drug delivery and translational research 2024 May;14(5):1352-1369
Drug delivery and translational research 2024 May;14(5):1352-1369
Mast cell-mediated inflammation relies on insulin-regulated aminopeptidase controlling cytokine export from the Golgi.
Weimershaus M, Carvalho C, Rignault R, Waeckel-Enee E, Dussiot M, van Endert P, Maciel TT, Hermine O
The Journal of allergy and clinical immunology 2023 Jun;151(6):1595-1608.e6
The Journal of allergy and clinical immunology 2023 Jun;151(6):1595-1608.e6
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
Zheng S, Lin J, Pang Z, Zhang H, Wang Y, Ma L, Zhang H, Zhang X, Chen M, Zhang X, Zhao C, Qi J, Cao L, Wang M, He X, Sheng R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Isogawa K, Asano M, Hayazaki M, Koga K, Watanabe M, Suzuki K, Kobayashi T, Kawaguchi K, Ishizuka A, Kato S, Ito H, Hamamoto A, Koyama H, Furuta K, Takemori H
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis.
Hamel Y, Mauvais FX, Madrange M, Renard P, Lebreton C, Nemazanyy I, Pellé O, Goudin N, Tang X, Rodero MP, Tuchmann-Durand C, Nusbaum P, Brindley DN, van Endert P, de Lonlay P
Cell reports. Medicine 2021 Aug 17;2(8):100370
Cell reports. Medicine 2021 Aug 17;2(8):100370
IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells.
Weimershaus M, Mauvais FX, Evnouchidou I, Lawand M, Saveanu L, van Endert P
Frontiers in cell and developmental biology 2020;8:585713
Frontiers in cell and developmental biology 2020;8:585713
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, Caillens V, Koumantou D, Lotersztajn S, van Endert P, Davoust J, Guermonprez P, Hivroz C, Gross DA, Saveanu L
Nature communications 2020 Jun 2;11(1):2779
Nature communications 2020 Jun 2;11(1):2779
Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
Malik N, Nirujogi RS, Peltier J, Macartney T, Wightman M, Prescott AR, Gourlay R, Trost M, Alessi DR, Karapetsas A
The Biochemical journal 2019 Oct 30;476(20):3081-3107
The Biochemical journal 2019 Oct 30;476(20):3081-3107
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338
Biophysics reports 2018;4(6):329-338
Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.
Weimershaus M, Mauvais FX, Saveanu L, Adiko C, Babdor J, Abramova A, Montealegre S, Lawand M, Evnouchidou I, Huber KJ, Chadt A, Zwick M, Vargas P, Dussiot M, Lennon-Dumenil AM, Brocker T, Al-Hasani H, van Endert P
Cell reports 2018 Sep 25;24(13):3568-3581
Cell reports 2018 Sep 25;24(13):3568-3581
MARCH9-mediated ubiquitination regulates MHC I export from the TGN.
De Angelis Rigotti F, De Gassart A, Pforr C, Cano F, N'Guessan P, Combes A, Camossetto V, Lehner PJ, Pierre P, Gatti E
Immunology and cell biology 2017 Oct;95(9):753-764
Immunology and cell biology 2017 Oct;95(9):753-764
IRAP(+) endosomes restrict TLR9 activation and signaling.
Babdor J, Descamps D, Adiko AC, Tohmé M, Maschalidi S, Evnouchidou I, Vasconcellos LR, De Luca M, Mauvais FX, Garfa-Traore M, Brinkmann MM, Chignard M, Manoury B, Saveanu L
Nature immunology 2017 May;18(5):509-518
Nature immunology 2017 May;18(5):509-518
Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.
Su X, Liang H, Wang H, Chen G, Jiang H, Wu Q, Liu T, Liu Q, Yu T, Gu Y, Yang B, Shan H
Scientific reports 2017 Apr 11;7:46259
Scientific reports 2017 Apr 11;7:46259
Poster Session Abstracts.
Pediatric pulmonology 2015 Oct;50 Suppl 41:S193-453
Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation.
Weimershaus M, Maschalidi S, Sepulveda F, Manoury B, van Endert P, Saveanu L
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1840-6
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1840-6
HID-1 is a peripheral membrane protein primarily associated with the medial- and trans- Golgi apparatus.
Wang L, Zhan Y, Song E, Yu Y, Jiu Y, Du W, Lu J, Liu P, Xu P, Xu T
Protein & cell 2011 Jan;2(1):74-85
Protein & cell 2011 Jan;2(1):74-85
IRAP identifies an endosomal compartment required for MHC class I cross-presentation.
Saveanu L, Carroll O, Weimershaus M, Guermonprez P, Firat E, Lindo V, Greer F, Davoust J, Kratzer R, Keller SR, Niedermann G, van Endert P
Science (New York, N.Y.) 2009 Jul 10;325(5937):213-7
Science (New York, N.Y.) 2009 Jul 10;325(5937):213-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10841-1-AP(STX6 antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-STX6 (IP:10841-1-AP, 3ug; Detection:10841-1-AP 1:1000) with mouse brain tissue lysate 7000ug.
- Sample type
- tissue