RGS8

This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]

Description

Regulator of G protein signaling 8

Tissue specificity

Group enriched (brain, retina)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

1 (182641816 - 182684576)

Ensembl ID

ENSG00000135824  (ver. 103.38)

Orthologs

Mouse Rgs8: ENSMUSG00000042671

UniProt

P57771

neXtProt

NX_P57771

Human splice variants
Mouse splice variants

Protein structure