Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5894 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RGS1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 161-206 of Human RGS1.
- Description
- Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein Ï«, ÉÇ and ÎÛ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Ï« subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several GÏ« GTPase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (GÏ«-interacting protein). Each of these proteins has been shown to deactivate specific GÏ« isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of GÏ« q function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate GÏ« t.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of RGS1 pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264.7 cell lysateLane3:H9C2 cell lysate