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- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10678-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10678-1-AP, RRID:AB_2284998
- Product name
- RGS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RGS2 antibody (Cat. #10678-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protective role of RGS2 in PM2.5-induced ovarian injury in rats: Modulation of Gq/11 signaling to maintain granulosa cell [Ca(2 +) ]i stability.
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
In Silico Design of Novel RGS2-G(alpha-q) Interaction Inhibitors with Anticancer Activity.
RGS2 attenuates alveolar macrophage damage by inhibiting the Gq/11-Ca(2+) pathway during cowshed PM2.5 exposure, and aberrant RGS2 expression is associated with TLR2/4 activation.
Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection.
RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
Novel role of Giα2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells.
Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
Ma Z, Du X, Zhao C, Sun Y, Jia Y, Liang X, Yu X, Gao Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118537
Ecotoxicology and environmental safety 2025 Sep 1;302:118537
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
Cheng L, Li H, Xie C, Kuang K, Wan B, Chen P, Sui H, Zhao Q, Cho N, Cui R
Bioorganic chemistry 2025 Oct;165:109010
Bioorganic chemistry 2025 Oct;165:109010
In Silico Design of Novel RGS2-G(alpha-q) Interaction Inhibitors with Anticancer Activity.
Bair A, Printy N, Choi SH, Wilkinson J, O'Brien J, Myers B, Roman D, Mahfouz TM
Journal of chemical information and modeling 2024 Oct 28;64(20):8052-8062
Journal of chemical information and modeling 2024 Oct 28;64(20):8052-8062
RGS2 attenuates alveolar macrophage damage by inhibiting the Gq/11-Ca(2+) pathway during cowshed PM2.5 exposure, and aberrant RGS2 expression is associated with TLR2/4 activation.
Ma Z, Du X, Sun Y, Sun K, Zhang X, Wang L, Zhu Y, Basang W, Gao Y
Toxicology and applied pharmacology 2024 Jun;487:116976
Toxicology and applied pharmacology 2024 Jun;487:116976
Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection.
Yuan LX, Yang B, Fung TS, Chen RA, Liu DX
Virology 2022 Oct;575:1-9
Virology 2022 Oct;575:1-9
RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
Cho J, Min HY, Lee HJ, Hyun SY, Sim JY, Noh M, Hwang SJ, Park SH, Boo HJ, Lee HJ, Hong S, Park RW, Shin YK, Hung MC, Lee HY
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
Novel role of Giα2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells.
Caggia S, Chunduri H, Millena AC, Perkins JN, Venugopal SV, Vo BT, Li C, Tu Y, Khan SA
Journal of cellular physiology 2018 Jan;234(1):802-815
Journal of cellular physiology 2018 Jan;234(1):802-815
Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.
Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel PW, Toews ML, Wolff DW, Rennard S, Panettieri RA Jr, Casale TB, Tu Y
Respiratory research 2016 Aug 22;17(1):103
Respiratory research 2016 Aug 22;17(1):103
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
Klaiber M, Kruse M, Völker K, Schröter J, Feil R, Freichel M, Gerling A, Feil S, Dietrich A, Londoño JE, Baba HA, Abramowitz J, Birnbaumer L, Penninger JM, Pongs O, Kuhn M
Basic research in cardiology 2010 Sep;105(5):583-95
Basic research in cardiology 2010 Sep;105(5):583-95
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 10678-1-AP(RGS2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RGS2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RGS2. This antibody recognizes human antigen. The RGS2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
