Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS6724 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RGS2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human RGS2.
- Description
- Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein a, b and g polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several Ga GTP-ase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (Gϫ-interacting protein). Each of these proteins has been shown to deactivate specific Gϫ isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of Gϫq function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate Gϫt.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of extracts of human brain cell lines, using RGS2 antibody.