Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 20359-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20359-1-AP, RRID:AB_10733224
- Product name
- PER2 antibody
- Antibody type
- Polyclonal
- Description
- PER2 antibody (Cat. #20359-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Phosphorylation of GAPVD1 Is Regulated by the PER Complex and Linked to GAPVD1 Degradation.
The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization.
Ruminal epithelial cell proliferation and short-chain fatty acid transporters in vitro are associated with abundance of period circadian regulator 2 (PER2).
Circadian oscillations persist in low malignancy breast cancer cells.
Pathophysiological significance of clock genes BMAL1 and PER2 as erythropoietin-controlling factors in acute blood hemorrhage.
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.
Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα.
Construction of recombinant pEGFP-N1-hPer2 plasmid and its expression in osteosarcoma cells.
Construction of a plasmid for overexpression of human circadian gene period2 and its biological activity in osteosarcoma cells.
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
Li R, Xiao J, Cao Y, Huang Q, Ho CT, Lu M
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.
Luo L, Li R, Wang G, Chen J, Chen L, Qin LQ, Yu Z, Wan Z
Food & function 2022 Apr 20;13(8):4445-4458
Food & function 2022 Apr 20;13(8):4445-4458
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Lee Y, Fong SY, Shon J, Zhang SL, Brooks R, Lahens NF, Chen D, Dang CV, Field JM, Sehgal A
Science advances 2021 Feb;7(7)
Science advances 2021 Feb;7(7)
Phosphorylation of GAPVD1 Is Regulated by the PER Complex and Linked to GAPVD1 Degradation.
Ibrahim H, Reus P, Mundorf AK, Grothoff AL, Rudenko V, Buschhaus C, Stefanski A, Berleth N, Stork B, Stühler K, Kalfalah F, Reinke H
International journal of molecular sciences 2021 Apr 6;22(7)
International journal of molecular sciences 2021 Apr 6;22(7)
The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization.
Zha M, Tian T, Xu W, Liu S, Jia J, Wang L, Yan Q, Li N, Yu J, Huang L
Cell death & disease 2020 Jun 10;11(6):446
Cell death & disease 2020 Jun 10;11(6):446
Ruminal epithelial cell proliferation and short-chain fatty acid transporters in vitro are associated with abundance of period circadian regulator 2 (PER2).
Gao J, Xu Q, Wang M, Ouyang J, Tian W, Feng D, Liang Y, Jiang B, Loor JJ
Journal of dairy science 2020 Dec;103(12):12091-12103
Journal of dairy science 2020 Dec;103(12):12091-12103
Circadian oscillations persist in low malignancy breast cancer cells.
Lellupitiyage Don SS, Lin HH, Furtado JJ, Qraitem M, Taylor SR, Farkas ME
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2447-2453
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2447-2453
Pathophysiological significance of clock genes BMAL1 and PER2 as erythropoietin-controlling factors in acute blood hemorrhage.
Tani N, Ikeda T, Aoki Y, Shida A, Oritani S, Ishikawa T
Human cell 2019 Jul;32(3):275-284
Human cell 2019 Jul;32(3):275-284
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV
Cell 2018 Jun 28;174(1):72-87.e32
Cell 2018 Jun 28;174(1):72-87.e32
NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.
Wible RS, Ramanathan C, Sutter CH, Olesen KM, Kensler TW, Liu AC, Sutter TR
eLife 2018 Feb 26;7
eLife 2018 Feb 26;7
Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα.
Altman BJ, Hsieh AL, Gouw AM, Dang CV
Nature communications 2017 Mar 23;8:14862
Nature communications 2017 Mar 23;8:14862
Construction of recombinant pEGFP-N1-hPer2 plasmid and its expression in osteosarcoma cells.
Cheng A, Zhang Y, Mei H, Fang S, Ji P, Yang J, Yu L, Guo W
Oncology letters 2016 Apr;11(4):2768-2772
Oncology letters 2016 Apr;11(4):2768-2772
Construction of a plasmid for overexpression of human circadian gene period2 and its biological activity in osteosarcoma cells.
Cheng AY, Zhang Y, Mei HJ, Fang S, Ji P, Yang J, Yu L, Guo WC
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 May;36(5):3735-43
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 May;36(5):3735-43
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV
Cell metabolism 2015 Dec 1;22(6):1009-19
Cell metabolism 2015 Dec 1;22(6):1009-19
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
Lee Y, Jang AR, Francey LJ, Sehgal A, Hogenesch JB
eLife 2015 Aug 29;4
eLife 2015 Aug 29;4
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 20359-1-AP(PER2 antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PER2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PER2. This antibody recognizes human antigen. The PER2 antibody has been validated for the following applications: ELISA, WB, IP analysis.