Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- H00117581-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00117581-M01, RRID:AB_548934
- Product name
- Mouse Monoclonal Twist-2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. TWIST2 - twist homolog 2 (Drosophila)
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references RNAi screen identifies essential regulators of human brain metastasis-initiating cells.
Expression of Twist2 is controlled by T-cell receptor signaling and determines the survival and death of thymocytes.
Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV.
Twist2 is a valuable prognostic biomarker for colorectal cancer.
Significance of heterogeneous Twist2 expression in human breast cancers.
Evaluation of prognostic factors in stage IIA breast tumors and their correlation with mortality risk.
Evaluation of prognostic factors in stage IIA breast tumors and their correlation with mortality risk.
Discordant gene expression signatures and related phenotypic differences in lamin A- and A/C-related Hutchinson-Gilford progeria syndrome (HGPS).
Twist2 contributes to breast cancer progression by promoting an epithelial-mesenchymal transition and cancer stem-like cell self-renewal.
Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.
Molecular mechanism of transforming growth factor-beta-mediated inhibition of growth arrest and differentiation in a myoblast cell line.
Singh M, Venugopal C, Tokar T, Brown KR, McFarlane N, Bakhshinyan D, Vijayakumar T, Manoranjan B, Mahendram S, Vora P, Qazi M, Dhillon M, Tong A, Durrer K, Murty N, Hallet R, Hassell JA, Kaplan DR, Cutz JC, Jurisica I, Moffat J, Singh SK
Acta neuropathologica 2017 Dec;134(6):923-940
Acta neuropathologica 2017 Dec;134(6):923-940
Expression of Twist2 is controlled by T-cell receptor signaling and determines the survival and death of thymocytes.
Oh S, Oh J, Lee C, Oh S, Jeon S, Choi J, Hwang S, Lee Y, Lee H, Seong RH
Cell death and differentiation 2016 Nov 1;23(11):1804-1814
Cell death and differentiation 2016 Nov 1;23(11):1804-1814
Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV.
Rodrigues IS, Lavorato-Rocha AM, de M Maia B, Stiepcich MM, de Carvalho FM, Baiocchi G, Soares FA, Rocha RM
British journal of cancer 2013 Jul 9;109(1):184-94
British journal of cancer 2013 Jul 9;109(1):184-94
Twist2 is a valuable prognostic biomarker for colorectal cancer.
Yu H, Jin GZ, Liu K, Dong H, Yu H, Duan JC, Li Z, Dong W, Cong WM, Yang JH
World journal of gastroenterology 2013 Apr 21;19(15):2404-11
World journal of gastroenterology 2013 Apr 21;19(15):2404-11
Significance of heterogeneous Twist2 expression in human breast cancers.
Mao Y, Zhang N, Xu J, Ding Z, Zong R, Liu Z
PloS one 2012;7(10):e48178
PloS one 2012;7(10):e48178
Evaluation of prognostic factors in stage IIA breast tumors and their correlation with mortality risk.
Carvalho ST, Stiepcich MM, Fregnani JH, Nonogaki S, Rocha R, Soares FA
Clinics (Sao Paulo, Brazil) 2011;66(4):607-12
Clinics (Sao Paulo, Brazil) 2011;66(4):607-12
Evaluation of prognostic factors in stage IIA breast tumors and their correlation with mortality risk.
Carvalho ST, Stiepcich MM, Fregnani JH, Nonogaki S, Rocha R, Soares FA
Clinics (Sao Paulo, Brazil) 2011;66(4):607-12
Clinics (Sao Paulo, Brazil) 2011;66(4):607-12
Discordant gene expression signatures and related phenotypic differences in lamin A- and A/C-related Hutchinson-Gilford progeria syndrome (HGPS).
Plasilova M, Chattopadhyay C, Ghosh A, Wenzel F, Demougin P, Noppen C, Schaub N, Szinnai G, Terracciano L, Heinimann K
PloS one 2011;6(6):e21433
PloS one 2011;6(6):e21433
Twist2 contributes to breast cancer progression by promoting an epithelial-mesenchymal transition and cancer stem-like cell self-renewal.
Fang X, Cai Y, Liu J, Wang Z, Wu Q, Zhang Z, Yang CJ, Yuan L, Ouyang G
Oncogene 2011 Nov 24;30(47):4707-20
Oncogene 2011 Nov 24;30(47):4707-20
Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.
Doreau A, Belot A, Bastid J, Riche B, Trescol-Biemont MC, Ranchin B, Fabien N, Cochat P, Pouteil-Noble C, Trolliet P, Durieu I, Tebib J, Kassai B, Ansieau S, Puisieux A, Eliaou JF, Bonnefoy-Bérard N
Nature immunology 2009 Jul;10(7):778-85
Nature immunology 2009 Jul;10(7):778-85
Molecular mechanism of transforming growth factor-beta-mediated inhibition of growth arrest and differentiation in a myoblast cell line.
Murakami M, Ohkuma M, Nakamura M
Development, growth & differentiation 2008 Feb;50(2):121-30
Development, growth & differentiation 2008 Feb;50(2):121-30
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Twist-2 Antibody (3C8) [H00117581-M01] - Analysis of TWIST2 expression in transfected 293T cell line by TWIST2 monoclonal antibody (M01), clone 3C8.Lane 1: TWIST2 transfected lysate(18.1 KDa).Lane 2: Non-transfected lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: Twist-2 Antibody (3C8) [H00117581-M01] - Detection limit for recombinant GST tagged TWIST2 is 0.3 ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Twist-2 Antibody (3C8) [H00117581-M01] - Immunoperoxidase of monoclonal antibody to TWIST2 ( Cat # H00117581-M01 ) on formalin-fixed paraffin-embedded human liver. [antibody concentration 3ug/ml]
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Twist-2 Antibody (3C8) [H00117581-M01] - Analysis of monoclonal antibody to TWIST2 on formalin-fixed paraffin-embedded human adrenal gland. Antibody concentration 3 ug/ml.