66358-1-Ig

antibody from Proteintech Group

Targeting: POMC ACTH, CLIP, LPH, MSH, NPP, POC

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

66358-1-Ig

Provider

Proteintech Group

Product name

POMC antibody

Antibody type

Monoclonal

Description

POMC antibody (Cat. #66358-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat, mouse, pig and has been validated for the following applications: FC, IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3C12C7

Vial size

20ul, 150ul

References

Submitted references

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Frontiers in pharmacology 2025;16:1730786

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Phenanthrene exposure disrupts puberty onset in SD rats by influencing hypothalamic neural networks.

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Acta histochemica 2025 Jun;127(2):152257

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Electroacupuncture alleviates insulin resistance and impacts the hypothalamic IRS-1/PI3K/AKT pathway and miRNA-29a-3p in a rat model of type 2 diabetes.

Zhuang S, Liu S, Li R, Duan H
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):104-113

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Effects of Electroacupuncture at Varied Frequencies on Analgesia and Mechanisms in Sciatic Nerve Cuffing-Induced Neuropathic Pain Mice.

Fang K, Cheng W, Yu B
Journal of molecular neuroscience : MN 2024 Oct 17;74(4):98

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Release of Lipids Stored in the Intestine by Glucagon-Like Peptide-2 Involves a Gut-Brain Neural Pathway.

Mukherjee K, Wang R, Xiao C
Arteriosclerosis, thrombosis, and vascular biology 2024 Jan;44(1):192-201

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Low-frequency electroacupuncture exerts antinociceptive effects through activation of POMC neural circuit induced endorphinergic input to the periaqueductal gray from the arcuate nucleus.

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Jiang Tang San Hao Formula exerts its anti-diabetic effect by affecting the gut-microbiota-brain axis.

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Microbiome and metabolome analyses indicate variations in the gut microbiota that disrupt regulation of appetite.

Qi R, Zhang B, Qiu X, Liu X, Bao S, Wang J, Wang Q, Yang Y, Yang H, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e70003

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Journal of hypertension 2024 Aug 1;42(8):1409-1420

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Jinkui Shenqi pills ameliorate diabetes by regulating hypothalamic insulin resistance and POMC/AgRP expression and activity.

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Tumor-derived semaphorin 3D promoting cancer cachexia via regulating hypothalamic pro-opiomelanocortin neurons.

Zhang Y, Xi Q, Zhong M, Jiang Y, Zhuang Q, Ding Z, Tan S, Wang J, Liu H, Zhang Z, Zhou B, Wu G
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Involvement of POMC neurons in LEAP2 regulation of food intake and body weight.

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FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs.

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Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.

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FoxO1 Regulates Neuropeptide Y and Pro-opiomelanocortin in the Hypothalamus of Rat Offspring Small for Gestational Age.

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919 syrup inhibits ROS-mediated leptin-induced anorexia by activating PPARγ and improves gut flora abnormalities.

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Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma.

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eLife 2021 Dec 14;10