Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 17060-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17060-1-AP, RRID:AB_2058998
- Product name
- ARL8A antibody
- Antibody type
- Polyclonal
- Description
- ARL8A antibody (Cat. #17060-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DENND6A links Arl8b to a Rab34/RILP/dynein complex, regulating lysosomal positioning and autophagy.
RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin.
The Salmonella effector SifA initiates a kinesin-1 and kinesin-3 recruitment process mirroring that mediated by Arl8a and Arl8b.
Specific KIF1A-adaptor interactions control selective cargo recognition.
ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1.
Kumar R, Khan M, Francis V, Aguila A, Kulasekaran G, Banks E, McPherson PS
Nature communications 2024 Jan 31;15(1):919
Nature communications 2024 Jan 31;15(1):919
RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin.
Keren-Kaplan T, Sarić A, Ghosh S, Williamson CD, Jia R, Li Y, Bonifacino JS
Nature communications 2022 Mar 21;13(1):1506
Nature communications 2022 Mar 21;13(1):1506
The Salmonella effector SifA initiates a kinesin-1 and kinesin-3 recruitment process mirroring that mediated by Arl8a and Arl8b.
Fang Z, Fallet M, Moest T, Gorvel JP, Méresse S
Journal of cell science 2022 Dec 1;135(1)
Journal of cell science 2022 Dec 1;135(1)
Specific KIF1A-adaptor interactions control selective cargo recognition.
Hummel JJA, Hoogenraad CC
The Journal of cell biology 2021 Oct 4;220(10)
The Journal of cell biology 2021 Oct 4;220(10)
ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1.
Keren-Kaplan T, Bonifacino JS
Current biology : CB 2021 Feb 8;31(3):540-554.e5
Current biology : CB 2021 Feb 8;31(3):540-554.e5
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ARL8A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ARL8A. This antibody recognizes human,mouse,rat antigen. The ARL8A antibody has been validated for the following applications: ELISA, WB analysis.
