12036-1-AP

antibody from Proteintech Group

Targeting: CHI3L1 GP39, YK-40, YKL40

Provider product page for 12036-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Immunohistochemistry [1]

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Product number: 12036-1-AP - Provider product page
Provider: Proteintech Group
Product name: CHI3L1/YKL40 antibody
Antibody type: Polyclonal
Description: CHI3L1/YKL40 antibody (Cat. #12036-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CHI3L1 protein structure - 12036-1-AP shown in red.

Submitted references Single-cell profile reveals the landscape of cardiac immunity and identifies a cardio-protective Ym-1(hi) neutrophil in myocardial ischemia-reperfusion injury.

Dong Y, Kang Z, Zhang Z, Zhang Y, Zhou H, Liu Y, Shuai X, Li J, Yin L, Wang X, Ma Y, Fan H, Jiang F, Lin Z, Ding C, Yun Jin K, Sarapultsev A, Li F, Zhang G, Xie T, Yin C, Cheng X, Luo S, Liu Y, Hu D
Science bulletin 2024 Apr 15;69(7):949-967

Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states.

Yao J, Dai S, Zhu R, Tan J, Zhao Q, Yin Y, Sun J, Du X, Ge L, Xu J, Hou C, Li N, Li J, Ji W, Zhu C, Zhang R, Li T
eLife 2024 Apr 12;12

ALKBH5-PYCR2 Positive Feedback Loop Promotes Proneural-Mesenchymal Transition Via Proline Synthesis In GBM.

Li L, Yang M, Pu X, Tang Y, Fei F, Li Z, Hou H, Chen Q, Wang Q, Wu Y, Zhang Y, Ren C, Gong A
Journal of Cancer 2023;14(9):1579-1591

CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation.

Jiang W, Zhu F, Xu H, Xu L, Li H, Yang X, Khan Afridi S, Lai S, Qiu X, Liu C, Li H, Long Y, Wang Y, Connolly K, Elias JA, Lee CG, Cui Y, Huang YA, Qiu W, Tang C
Science advances 2023 Sep 29;9(39):eadg8148

Epithelial Membrane Protein-3 and Chitinase-3-like Protein-1 as New Prognostic Predictors of Glioma, a Two-Gene Study.

Shen K, Zhu J, Zhou S, Jin X, Zhai W, Sun L, Wu J, Yu Z
Current oncology (Toronto, Ont.) 2023 Sep 23;30(10):8686-8702

CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis.

Sun Y, Shan X, Guo J, Liu X, Ma D
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1436-1451

Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.

Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838

Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.

Dai L, Gao F, Wang Q, Lv X, Cheng Z, Wu Y, Chai X, Zetterberg H, Blennow K, Levey AI, Shi J, Shen Y, CANDI Consortium
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559

The immune landscape of human thymic epithelial tumors.

Xin Z, Lin M, Hao Z, Chen D, Chen Y, Chen X, Xu X, Li J, Wu D, Chai Y, Wu P
Nature communications 2022 Sep 17;13(1):5463

Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer.

Johansen AZ, Carretta M, Thorseth ML, Khan S, Fjæstad KY, Brøchner CB, Linder H, Ankjærgaard C, Donia M, Chen I, Nielsen DL, Behrens CP, Madsen DH
Pharmaceutics 2022 May 12;14(5)

Differential expression of Chitinase 3-Like 1 protein in appendicitis and appendix carcinomas.

Zhang Y, Li Y, Li F, Li L, Wang C, Wang H, Chen Y, Zhang C, Zhang Y, Wang W
Journal of clinical laboratory analysis 2022 Dec;36(12):e24790

Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.

Zhang H, Zhang N, Dai Z, Wang Z, Zhang X, Liang X, Zhang L, Feng S, Wu W, Ye W, Zhang J, Luo P, Liu Z, Cheng Q, Liu Z
Molecular oncology 2022 Dec;16(22):3927-3948

Effects of chitinase-3-like protein 1 on brain death-induced hepatocyte apoptosis via PAR2-JNK-caspase-3.

Li ZX, Yang DJ, Huo ZK, Wen PH, Hu BW, Wang ZH, Guo WZ, Zhang SJ
Biochemical and biophysical research communications 2021 May 7;552:150-156

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.

Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X, Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C
eLife 2021 Jun 10;10

MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.

Shi Y, He W, Zhong M, Yu M
Genomics 2021 Jul;113(4):1988-1998

LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.

Liu W, Yang YJ, An Q
Cancer management and research 2020;12:463-473

BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.

Sha Z, Zhou J, Wu Y, Zhang T, Li C, Meng Q, Musunuru PP, You F, Wu Y, Yu R, Gao S
Frontiers in oncology 2020;10:565225

SSEA-4 and YKL-40 positive progenitor subtypes in the subventricular zone of developing human neocortex.

Brøchner CB, Møllgård K
Glia 2016 Jan;64(1):90-104

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The CHI3L1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CHI3L1. This antibody recognizes human,mouse,rat antigen. The CHI3L1 antibody has been validated for the following applications: ELISA, IHC analysis.
Appendix: 12036-1-AP.pdf

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