MAB507

antibody from R&D Systems

Targeting: BMP6 VGR, VGR1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB507

Provider

R&D Systems

Product name

Anti-Human BMP-6 Monoclonal Antibody (Clone 74219)

Antibody type

Monoclonal

Antigen

Chinese hamster ovary cell line CHO-derived recombinant human BMP-6, Arg296-His428

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

Q4VBA3


Isotype

IgG

Vial size

500 µg

References

Submitted references

Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer.

Blanchette-Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, Claffey KP, Torti FM, Torti SV
Oncogene 2018 Jul;37(29):4013-4032

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TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

Hurst LA, Dunmore BJ, Long L, Crosby A, Al-Lamki R, Deighton J, Southwood M, Yang X, Nikolic MZ, Herrera B, Inman GJ, Bradley JR, Rana AA, Upton PD, Morrell NW
Nature communications 2017 Jan 13;8:14079

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Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.

Meynard D, Vaja V, Sun CC, Corradini E, Chen S, López-Otín C, Grgurevic L, Hong CC, Stirnberg M, Gütschow M, Vukicevic S, Babitt JL, Lin HY
Blood 2011 Jul 21;118(3):747-56

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Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.

Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET
Cancer research 2005 Sep 15;65(18):8274-85