Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 25821-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- STK25 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STK25 antibody (Cat. #25821-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular Carcinoma.
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways.
Downregulation of STK25 promotes autophagy via the Janus kinase 2/signal transducer and activator of transcription 3 pathway in colorectal cancer.
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease.
STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer.
Xia Y, Caputo M, Andersson E, Asiedu B, Zhang J, Hou W, Amrutkar M, Cansby E, Gul N, Gemmink A, Myers C, Aghajan M, Booten S, Hoy AJ, Härtlova A, Lindahl P, Ståhlberg A, Schaart G, Hesselink MKC, Peter A, Murray S, Mahlapuu M
Cellular and molecular gastroenterology and hepatology 2025;19(7):101485
Cellular and molecular gastroenterology and hepatology 2025;19(7):101485
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Thimme Gowda C, Siraganahalli Eshwaraiah M, Wang J, Lim Y, Tomasi ML, Mavila N, Ramani K
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
Song Z, Mao H, Liu J, Sun W, Wu S, Lu X, Jin C, Yang J
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways.
Kurhe Y, Caputo M, Cansby E, Xia Y, Kumari S, Anand SK, Howell BW, Marschall HU, Mahlapuu M
Cellular and molecular gastroenterology and hepatology 2022;13(2):405-423
Cellular and molecular gastroenterology and hepatology 2022;13(2):405-423
Downregulation of STK25 promotes autophagy via the Janus kinase 2/signal transducer and activator of transcription 3 pathway in colorectal cancer.
Chen J, Gao P, Peng L, Liu T, Wu F, Xu K, Chen L, Tan F, Xing P, Wang Z, Di J, Jiang B, Su X
Molecular carcinogenesis 2022 Jun;61(6):572-586
Molecular carcinogenesis 2022 Jun;61(6):572-586
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Zhou Z, Li H, Bai S, Xu Z, Jiao Y
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease.
Cansby E, Nuñez-Durán E, Magnusson E, Amrutkar M, Booten SL, Kulkarni NM, Svensson LT, Borén J, Marschall HU, Aghajan M, Mahlapuu M
Cellular and molecular gastroenterology and hepatology 2019;7(3):597-618
Cellular and molecular gastroenterology and hepatology 2019;7(3):597-618
STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer.
Wu F, Gao P, Wu W, Wang Z, Yang J, Di J, Jiang B, Su X
Journal of experimental & clinical cancer research : CR 2018 Jul 11;37(1):144
Journal of experimental & clinical cancer research : CR 2018 Jul 11;37(1):144
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 25821-1-AP( STK25 Antibody) at dilution of 1:600
- Other comments
- WB