V2733

antibody from NSJ Bioreagents

Targeting: MUC5AC MUC5

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

V2733

Provider

NSJ Bioreagents

Product name

MUC5AC Antibody

Antibody type

Monoclonal

Antigen

An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for the MUC5AC antibody.

Description

Protein G purified antibody

Reactivity

Human, Mouse, Rat, Bovine, Feline, Rabbit, Simian

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

1-13M1

Vial size

20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)

Storage

Store the MUC5AC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

References

Submitted references

Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: a promising biomarker and therapeutic target for pancreatic cancer.

Liu D, Chang CH, Gold DV, Goldenberg DM
Oncotarget 2015 Feb 28;6(6):4274-85

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The relationship between mucin phenotype and clinicopathological factors, proliferative activity and p53 expression in gastric hyperplastic polyps.

Li J, Wu LH, Shi Y, Li HM, Song MY, Jiao YF
Histology and histopathology 2014 Mar;29(3):343-51

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Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue.

Haslene-Hox H, Oveland E, Woie K, Salvesen HB, Wiig H, Tenstad O
Biochimica et biophysica acta 2013 Nov;1834(11):2347-59

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Low-methoxyl pectin stimulates small intestinal mucin secretion irrespective of goblet cell proliferation and is characterized by jejunum Muc2 upregulation in rats.

Hino S, Sonoyama K, Bito H, Kawagishi H, Aoe S, Morita T
The Journal of nutrition 2013 Jan;143(1):34-40

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Mucin5B expression by lung alveolar macrophages is increased in long-term smokers.

Sepper R, Prikk K, Metsis M, Sergejeva S, Pugatsjova N, Bragina O, Marran S, Fehniger TE
Journal of leukocyte biology 2012 Aug;92(2):319-24

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Naegleria fowleri induces MUC5AC and pro-inflammatory cytokines in human epithelial cells via ROS production and EGFR activation.

Cervantes-Sandoval I, Serrano-Luna Jde J, Meza-Cervantez P, Arroyo R, Tsutsumi V, Shibayama M
Microbiology (Reading, England) 2009 Nov;155(Pt 11):3739-47

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Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin.

Lidell ME, Bara J, Hansson GC
The FEBS journal 2008 Feb;275(3):481-9

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Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme.

Shao MX, Nadel JA
Journal of immunology (Baltimore, Md. : 1950) 2005 Sep 15;175(6):4009-16

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E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells.

Kim S, Schein AJ, Nadel JA
American journal of physiology. Lung cellular and molecular physiology 2005 Dec;289(6):L1049-60

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Mapping of SOMU1 and M1 epitopes on the apomucin encoded by the 5' end of the MUC5AC gene.

Nollet S, Escande F, Buisine MP, Forgue-Lafitte ME, Kirkham P, Okada Y, Bara J
Hybridoma and hybridomics 2004 Apr;23(2):93-9