Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- V2739 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- MUC5AC Antibody
- Antibody type
- Monoclonal
- Antigen
- An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for the MUC5AC antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Bovine, Feline, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 2-11M1
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the MUC5AC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Expression and characterization of a novel recombinant version of the secreted human mucin MUC5AC in airway cell lines.
Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: a promising biomarker and therapeutic target for pancreatic cancer.
Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway.
Proteases present in some pancreatic cyst fluids may affect mucin immunoassay by degrading antibodies and antigens.
Mucin biosynthesis in the bovine goblet cell induced by Cooperia oncophora infection.
Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin.
Ryan A, Smith A, Moore P, McNally S, Carrington SD, Reid CJ, Clyne M
Biochemistry 2015 Feb 3;54(4):1089-99
Biochemistry 2015 Feb 3;54(4):1089-99
Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: a promising biomarker and therapeutic target for pancreatic cancer.
Liu D, Chang CH, Gold DV, Goldenberg DM
Oncotarget 2015 Feb 28;6(6):4274-85
Oncotarget 2015 Feb 28;6(6):4274-85
Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway.
Song S, Byrd JC, Guha S, Liu KF, Koul D, Bresalier RS
Cancer 2011 Jun 1;117(11):2386-97
Cancer 2011 Jun 1;117(11):2386-97
Proteases present in some pancreatic cyst fluids may affect mucin immunoassay by degrading antibodies and antigens.
Forgue-Lafitte ME, Arambam R, Bara J
Pancreas 2010 Oct;39(7):1070-6
Pancreas 2010 Oct;39(7):1070-6
Mucin biosynthesis in the bovine goblet cell induced by Cooperia oncophora infection.
Li RW, Li C, Elsasser TH, Liu G, Garrett WM, Gasbarre LC
Veterinary parasitology 2009 Nov 12;165(3-4):281-9
Veterinary parasitology 2009 Nov 12;165(3-4):281-9
Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin.
Lidell ME, Bara J, Hansson GC
The FEBS journal 2008 Feb;275(3):481-9
The FEBS journal 2008 Feb;275(3):481-9
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free MUC5AC Antibody (clone 2-11M1). Confirmation of Integrity and Purity of the Antibody.