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- References [13]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12023-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12023-2-AP, RRID:AB_906407
- Product name
- NUCKS1 antibody
- Antibody type
- Polyclonal
- Description
- NUCKS1 antibody (Cat. #12023-2-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells.
NUCKS1 exacerbates hepatocellular carcinoma cell proliferation and metastasis via the upregulation of Cdc42.
SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging.
NUCKS1 promotes invasion and metastasis of colorectal cancer by stabilizing HDAC2 and activating AKT.
BDNF improves fracture healing through promoting osteoblasts proliferation and migration via trkb/akt regulated NUCKS1 expression.
NUCKS1, a gene targeted by miR-497-5p, suppresses the antitumor effect of Brusatol and enhances malignancy of HNSCC via upregulating S100A9 expression.
NUCB2 inhibition antagonizes osteosarcoma progression and promotes anti-tumor immunity through inactivating NUCKS1/CXCL8 axis.
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
NUCKS1, a LINC00629-upregulated gene, facilitated osteosarcoma progression and metastasis by elevating asparagine synthesis.
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
The NUCKS1-SKP2-p21/p27 axis controls S phase entry.
NUCKS promotes cell proliferation and suppresses autophagy through the mTOR-Beclin1 pathway in gastric cancer.
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Feng H, Li Z, Zhang H, Zheng Y, Xu B, Zhang Y, Zou L, Wu L
Nucleic acids research 2026 Feb 5;54(4)
Nucleic acids research 2026 Feb 5;54(4)
NUCKS1 exacerbates hepatocellular carcinoma cell proliferation and metastasis via the upregulation of Cdc42.
Fan W, Ma Y, Wu J, Zhang X
American journal of cancer research 2025;15(3):1051-1065
American journal of cancer research 2025;15(3):1051-1065
SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging.
Tran KA, Gilbert M, Vazquez BN, Ianni A, Garcia BA, Vaquero A, Berger SL
Molecular cell 2025 Jun 19;85(12):2390-2408.e6
Molecular cell 2025 Jun 19;85(12):2390-2408.e6
NUCKS1 promotes invasion and metastasis of colorectal cancer by stabilizing HDAC2 and activating AKT.
Zhu L, Zhao T, Su H, Li J, Shen X, Zhang L, Chen J, Song Y
Oncogenesis 2025 Jun 17;14(1):19
Oncogenesis 2025 Jun 17;14(1):19
BDNF improves fracture healing through promoting osteoblasts proliferation and migration via trkb/akt regulated NUCKS1 expression.
Meng W, Meng X, Han C, Li Y, Qian X, Zhang Z
Scientific reports 2025 Jul 25;15(1):27107
Scientific reports 2025 Jul 25;15(1):27107
NUCKS1, a gene targeted by miR-497-5p, suppresses the antitumor effect of Brusatol and enhances malignancy of HNSCC via upregulating S100A9 expression.
Ma C, Song J, Feng H, Kui X, Liu S, Shi S, Li X, Tang L
Biochemical pharmacology 2025 Dec;242(Pt 2):117328
Biochemical pharmacology 2025 Dec;242(Pt 2):117328
NUCB2 inhibition antagonizes osteosarcoma progression and promotes anti-tumor immunity through inactivating NUCKS1/CXCL8 axis.
Ji R, Wang Y, Pan D, Han J, Wang Y, Zheng S, Zhao W, Li X, Han C, Zhang L
Cancer letters 2024 Jun 1;591:216893
Cancer letters 2024 Jun 1;591:216893
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Yao Y, Chen C, Wang J, Xuan H, Chen X, Li Z, Yang F, Wang B, Lin S, Li S, Tang D, Gong L, Gao W
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
NUCKS1, a LINC00629-upregulated gene, facilitated osteosarcoma progression and metastasis by elevating asparagine synthesis.
Zheng S, Ji R, He H, Li N, Han C, Han J, Li X, Zhang L, Wang Y, Zhao W
Cell death & disease 2023 Aug 1;14(8):489
Cell death & disease 2023 Aug 1;14(8):489
NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.
Zhu LL, Shi JJ, Guo YD, Yang C, Wang RL, Li SS, Gan DX, Ma PX, Li JQ, Su HC
Neoplasma 2023 Apr;70(2):272-286
Neoplasma 2023 Apr;70(2):272-286
The NUCKS1-SKP2-p21/p27 axis controls S phase entry.
Hume S, Grou CP, Lascaux P, D'Angiolella V, Legrand AJ, Ramadan K, Dianov GL
Nature communications 2021 Nov 29;12(1):6959
Nature communications 2021 Nov 29;12(1):6959
NUCKS promotes cell proliferation and suppresses autophagy through the mTOR-Beclin1 pathway in gastric cancer.
Zhao E, Feng L, Bai L, Cui H
Journal of experimental & clinical cancer research : CR 2020 Sep 21;39(1):194
Journal of experimental & clinical cancer research : CR 2020 Sep 21;39(1):194
NUCKS1 is a novel regulator of milk synthesis in and proliferation of mammary epithelial cells via the mTOR signaling pathway.
Yuan X, Zhang M, Ao J, Zhen Z, Gao X, Li M
Journal of cellular physiology 2019 Sep;234(9):15825-15835
Journal of cellular physiology 2019 Sep;234(9):15825-15835
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SGC-7901 cells were subjected to SDS PAGE followed by western blot with 12023-2-AP(NUCKS1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NUCKS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NUCKS1. This antibody recognizes human,mouse,rat antigen. The NUCKS1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
