Antibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Other assay [1]
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- Product number
- PA5-46903 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-19 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.2 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.
He Y, Luo W, Liu Y, Wang Y, Ma C, Wu Q, Tian P, He D, Jia Z, Lv X, Ma YS, Yang H, Xu K, Zhang X, Xiao Y, Zhang P, Liang Y, Fu D, Yao F, Hu G
The Journal of clinical investigation 2022 Oct 17;132(20)
The Journal of clinical investigation 2022 Oct 17;132(20)
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Neutralization of IL-19 in BaF3 mouse pro‚B cell line co-transfected with human IL‚20 Rα and IL‚20 Rβ. Samples were incubated in IL-19 polyclonal antibody (Product # PA5-46903). Recombinant Human IL‚19 stimulates proliferation in the BaF3 mouse pro‚B cell line co-transfected with human IL‚20 Rα and IL‚20 Rβ in a dose‚dependent manner (orange line). Proliferation elicited by Recombinant Human IL‚19 (3 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL‚19 Antigen Affinity-purified Polyclonal Antibody. The ND50 is typically 1-3 µg/mL.