ABIN951451

antibody from antibodies-online

Targeting: DTL CDT2, DCAF2, L2DTL, RAMP

Western blot (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN951451

Provider

antibodies-online

Product name

anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila) (DTL) (AA 229-256), (Middle Region) antibody

Antibody type

Polyclonal

Description

Affinity Chromatography on Protein A

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 229-256, Middle Region

Vial size

0.4 mL

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.

Abbas T, Shibata E, Park J, Jha S, Karnani N, Dutta A
Molecular cell 2010 Oct 8;40(1):9-21

---

CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.

Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L
Molecular cell 2010 Oct 8;40(1):22-33

---

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A
Genes & development 2008 Sep 15;22(18):2496-506

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Flow cytometry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS