Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12675-2-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12675-2-AP, RRID:AB_2252956
- Product name
- PPP2R5A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PPP2R5A antibody (Cat. #12675-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity.
Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DEAD-box helicase 5-activating transcription factor 1-protein phosphatase 2 regulatory subunit 5A signaling.
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.
Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer's disease mice.
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
PP2A promotes apoptosis and facilitates docetaxel sensitivity via the PP2A/p-eIF4B/XIAP signaling pathway in prostate cancer.
MicroRNA-218 promotes cisplatin resistance in oral cancer via the PPP2R5A/Wnt signaling pathway.
Li Y, Huang Y, Wang S, Xia H, Li J, Wu X, Lu Y, Ma B, Su G, Li Y
Bioorganic chemistry 2026 Jun 15;174:109684
Bioorganic chemistry 2026 Jun 15;174:109684
Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DEAD-box helicase 5-activating transcription factor 1-protein phosphatase 2 regulatory subunit 5A signaling.
Fan D, Zhong Y, Dong Y, Du M, Huang K, Li X
Journal of advanced research 2026 Jan;79:661-677
Journal of advanced research 2026 Jan;79:661-677
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
Yin H, Jiang H, Zhao R, Zhang Y, Fan X, Zhai X, Yang X, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.
Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W, Song M
Science advances 2025 Aug 22;11(34):eadv6937
Science advances 2025 Aug 22;11(34):eadv6937
Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer's disease mice.
Huang HZ, Ai WQ, Wei N, Zhu LS, Liu ZQ, Zhou CW, Deng MF, Zhang WT, Zhang JC, Yang CQ, Hu YZ, Han ZT, Zhang HH, Jia JJ, Wang J, Liu FF, Li K, Xu Q, Yuan M, Man H, Guo Z, Lu Y, Shu K, Zhu LQ, Liu D
Protein & cell 2024 Apr 1;15(4):261-284
Protein & cell 2024 Apr 1;15(4):261-284
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785
Cell death & disease 2022 Sep 12;13(9):785
PP2A promotes apoptosis and facilitates docetaxel sensitivity via the PP2A/p-eIF4B/XIAP signaling pathway in prostate cancer.
Yin S, Chen Y, Tong H, Li T, Qin Z, Zhu J, He W
Oncology letters 2022 Mar;23(3):101
Oncology letters 2022 Mar;23(3):101
MicroRNA-218 promotes cisplatin resistance in oral cancer via the PPP2R5A/Wnt signaling pathway.
Zhuang Z, Hu F, Hu J, Wang C, Hou J, Yu Z, Wang TT, Liu X, Huang H
Oncology reports 2017 Oct;38(4):2051-2061
Oncology reports 2017 Oct;38(4):2051-2061
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human ileum tissue were subjected to SDS PAGE followed by western blot with 12675-2-AP(PPP2R5A antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PPP2R5A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PPP2R5A. This antibody recognizes human,mouse,rat antigen. The PPP2R5A antibody has been validated for the following applications: ELISA, WB, IHC analysis.