Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 21290-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21290-1-AP, RRID:AB_10733881
- Product name
- SMYD2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SMYD2 antibody (Cat. #21290-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SMYD2 suppresses p53 activity to promote glucose metabolism in cervical cancer.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells Through Mediating the Transcriptional Activation of Key Mesendodermal Genes.
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Positive Expression of SMYD2 is Associated with Poor Prognosis in Patients with Primary Hepatocellular Carcinoma.
Wang Y, Jin G, Guo Y, Cao Y, Niu S, Fan X, Zhang J
Experimental cell research 2021 Jul 15;404(2):112649
Experimental cell research 2021 Jul 15;404(2):112649
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Yan L, Ding B, Liu H, Zhang Y, Zeng J, Hu J, Yao W, Yu G, An R, Chen Z, Ye Z, Xing J, Xiao K, Wu L, Xu H
Theranostics 2019;9(26):8377-8391
Theranostics 2019;9(26):8377-8391
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Lin Y, Liang A, He Y, Li Z, Li Z, Wang G, Sun F
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Molecular reproduction and development 2019 Sep;86(9):1094-1105
SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells Through Mediating the Transcriptional Activation of Key Mesendodermal Genes.
Bai HJ, Zhang P, Ma L, Liang H, Wei G, Yang HT
Stem cells (Dayton, Ohio) 2019 Nov;37(11):1401-1415
Stem cells (Dayton, Ohio) 2019 Nov;37(11):1401-1415
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Zeng Y, Qiu R, Yang Y, Gao T, Zheng Y, Huang W, Gao J, Zhang K, Liu R, Wang S, Hou Y, Yu W, Leng S, Feng D, Liu W, Zhang X, Wang Y
Cell reports 2019 Nov 5;29(6):1482-1498.e4
Cell reports 2019 Nov 5;29(6):1482-1498.e4
Positive Expression of SMYD2 is Associated with Poor Prognosis in Patients with Primary Hepatocellular Carcinoma.
Zuo SR, Zuo XC, He Y, Fang WJ, Wang CJ, Zou H, Chen P, Huang LF, Huang LH, Xiang H, Liu SK
Journal of Cancer 2018;9(2):321-330
Journal of Cancer 2018;9(2):321-330
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 21290-1-AP(SMYD2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using SMYD2 antibody 21290-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 21290-1-AP(SMYD2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue