10-4111

antibody from ABEOMICS Inc.
Targeting: S100A8 60B8AG, CAGA, CFAG, CGLA, MRP8, P8
Provider product page for 10-4111

Antibody data

Product number
10-4111 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-S100A8 Antibody
Antibody type
Monoclonal
Description
S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
Full length recombinant S100A8 prot
ein was used as the immunogen for t
his antibody.
Isotype
IgG
Antibody clone number
ABM4D13
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
S100A8 protein structure - 10-4111 shown in red.