Antibody data

Product number
PA5-55734
Provider
Invitrogen Antibodies
Product name
AIDA Polyclonal Antibody
Provider product page
Invitrogen Antibodies - PA5-55734
Antibody type
Polyclonal
Antigen
Recombinant full-length protein
Description
Mitochrondrial cytochrome c is a water-soluble protein of 15 kDa with a net positive charge, residing loosely attached in the mitochrondrial intermembrane space. Cytochrome c functions in the respiratory chain by interaction with redox partners. The release of cytochrome c into the cytosol leads to an activation of an apoptotic program via activation of a caspase dependent pathway. Cytochrome c achieves this goal by interaction with other cytosolic factors forming a complex (apoptosome) composed of cytochrome c, Apaf-1, dATP and Apaf-3/caspase 9. Bcl-2 on the other hand was shown to be able to prevent apoptosis by blocking the release of cytochrome c from mitochondria.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100 µL
Concentration
0.05 mg/mL
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.