Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10851-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10851-1-AP, RRID:AB_2209210
- Product name
- TRIM11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM11 antibody (Cat. #10851-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.
The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.
Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals.
TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.
Zhang ZY, Harischandra DS, Wang R, Ghaisas S, Zhao JY, McMonagle TP, Zhu G, Lacuarta KD, Song J, Trojanowski JQ, Xu H, Lee VM, Yang X
Science (New York, N.Y.) 2023 Jul 28;381(6656):eadd6696
Science (New York, N.Y.) 2023 Jul 28;381(6656):eadd6696
Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
Jin X, Shao X, Pang W, Wang Z, Huang J
Bioengineered 2022 May;13(5):13033-13044
Bioengineered 2022 May;13(5):13033-13044
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Zhang Y, Liu Q, Ning J, Jiang T, Kang A, Li L, Pang Y, Zhang B, Huang X, Wang Q, Bao L, Niu Y, Zhang R
Journal of hazardous materials 2022 Jun 15;432:128655
Journal of hazardous materials 2022 Jun 15;432:128655
Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.
He F, Wu Z, Wang Y, Yin L, Lu S, Dai L
Cell biology international 2022 Jan;46(1):148-157
Cell biology international 2022 Jan;46(1):148-157
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
Tang J, Tian Z, Liao X, Wu G
International journal of biological sciences 2021;17(2):417-429
International journal of biological sciences 2021;17(2):417-429
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, Wu G
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
Song Z, Guo Q, Wang H, Gao L, Wang S, Liu D, Liu J, Qi Y, Lin B
Pathology, research and practice 2020 Nov;216(11):153148
Pathology, research and practice 2020 Nov;216(11):153148
Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.
Wang Z, Xu X, Tang W, Zhu Y, Hu J, Zhang X
BioMed research international 2019;2019:9612125
BioMed research international 2019;2019:9612125
The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.
Chen W, Peng R, Sun Y, Liu H, Zhang L, Peng H, Zhang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Oct;33(10):11492-11506
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Oct;33(10):11492-11506
Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals.
Stittrich AB, Ashworth J, Shi M, Robinson M, Mauldin D, Brunkow ME, Biswas S, Kim JM, Kwon KS, Jung JU, Galas D, Serikawa K, Duerr RH, Guthery SL, Peschon J, Hood L, Roach JC, Glusman G
Human genome variation 2016;3:15060
Human genome variation 2016;3:15060
TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.
Di K, Linskey ME, Bota DA
Oncogene 2013 Oct 17;32(42):5038-47
Oncogene 2013 Oct 17;32(42):5038-47
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10851-1-AP(TRIM11 antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRIM11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRIM11. This antibody recognizes human antigen. The TRIM11 antibody has been validated for the following applications: ELISA, WB, IHC analysis.