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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11375-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11375-1-AP, RRID:AB_763171
- Product name
- FH antibody
- Antibody type
- Polyclonal
- Description
- FH antibody (Cat. #11375-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Eosinophilic Solid and Cystic Renal Cell Carcinoma: Morphologic and Immunohistochemical Study of 18 Cases and Review of the Literature.
Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation.
Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ.
Fumarate induces LncRNA-MIR4435-2HG to regulate glutamine metabolism remodeling and promote the development of FH-deficient renal cell carcinoma.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Circulating succinate-modifying metabolites accurately classify and reflect the status of fumarate hydratase-deficient renal cell carcinoma.
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter.
Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro.
Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E(2) alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field.
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Bioinformatics analysis and expression study of fumarate hydratase in lung cancer.
Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss.
Guo Q, Yao X, Yang B, Qi L, Wang F, Guo Y, Liu Y, Cao Z, Wang Y, Wang J, Li L, Huang Q, Liu C, Qu T, Zhao W, Ren D, Yang M, Yan C, Meng B, Wang C, Cao W
Archives of pathology & laboratory medicine 2024 Oct 1;148(10):1126-1134
Archives of pathology & laboratory medicine 2024 Oct 1;148(10):1126-1134
Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation.
Zhang Y, Jiang H, Dong M, Min J, He X, Tan Y, Liu F, Chen M, Chen X, Yin Q, Zheng L, Shao Y, Li X, Chen H
Cell reports 2024 May 28;43(5):114180
Cell reports 2024 May 28;43(5):114180
Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ.
Shibata T, Bhat SA, Cao D, Saito S, Bernstein EA, Nishi E, Medenilla JD, Wang ET, Chan JL, Pisarska MD, Tourtellotte WG, Giani JF, Bernstein KE, Khan Z
The Journal of biological chemistry 2024 Jan;300(1):105486
The Journal of biological chemistry 2024 Jan;300(1):105486
Fumarate induces LncRNA-MIR4435-2HG to regulate glutamine metabolism remodeling and promote the development of FH-deficient renal cell carcinoma.
Zhu L, Hong Y, Zhu Z, Huang J, Wang J, Li G, Wu X, Chen Y, Xu Y, Zheng L, Huang Y, Kong W, Xue W, Zhang J
Cell death & disease 2024 Feb 19;15(2):151
Cell death & disease 2024 Feb 19;15(2):151
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Circulating succinate-modifying metabolites accurately classify and reflect the status of fumarate hydratase-deficient renal cell carcinoma.
Zheng L, Zhu ZR, Sneh T, Zhang WT, Wang ZY, Wu GY, He W, Qi HG, Wang H, Wu XY, Fernández-García J, Abramovich I, Xu YZ, Zhang J, Gottlieb E
The Journal of clinical investigation 2023 Jun 1;133(11)
The Journal of clinical investigation 2023 Jun 1;133(11)
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Yuan M, Wang Y, Wen J, Jing F, Zou Q, Pu Y, Pan T, Cai Z
Aging and disease 2022 Oct 1;13(5):1532-1545
Aging and disease 2022 Oct 1;13(5):1532-1545
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter.
Shi F, Zhou M, Shang L, Du Q, Li Y, Xie L, Liu X, Tang M, Luo X, Fan J, Zhou J, Gao Q, Qiu S, Wu W, Zhang X, Bode AM, Cao Y
Theranostics 2019;9(9):2424-2438
Theranostics 2019;9(9):2424-2438
Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro.
Fan Z, Li L, Li X, Zhang M, Dou M, Zhao J, Cao J, Deng X, Zhang M, Li H, Suo Z
Aging 2019 Jan 21;11(2):573-589
Aging 2019 Jan 21;11(2):573-589
Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E(2) alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field.
Sun Y, Shi Z, Wang Y, Tang C, Liao Y, Yang C, Cai P
International journal of radiation biology 2018 Dec;94(12):1159-1166
International journal of radiation biology 2018 Dec;94(12):1159-1166
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, Cheng R, Zhang Y, Zhang X, Chen H, Huang B, Cao Y
Oncotarget 2017 Dec 26;8(69):114328-114343
Oncotarget 2017 Dec 26;8(69):114328-114343
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Ma X, Li C, Sun L, Huang D, Li T, He X, Wu G, Yang Z, Zhong X, Song L, Gao P, Zhang H
Nature communications 2014 Oct 10;5:5212
Nature communications 2014 Oct 10;5:5212
Bioinformatics analysis and expression study of fumarate hydratase in lung cancer.
Ming Z, Jiang M, Li W, Fan N, Deng W, Zhong Y, Zhang Y, Zhang Q, Yang S
Thoracic cancer 2014 Nov;5(6):543-9
Thoracic cancer 2014 Nov;5(6):543-9
Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss.
Coupland SE, Vorum H, Mandal N, Kalirai H, Honoré B, Urbak SF, Lake SL, Dopierala J, Damato B
Investigative ophthalmology & visual science 2010 Jan;51(1):12-20
Investigative ophthalmology & visual science 2010 Jan;51(1):12-20
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11375-1-AP(FH antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FH antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FH. This antibody recognizes human, mouse, rat antigen. The FH antibody has been validated for the following applications: ELISA, WB, IHC analysis.
