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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 60029-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60029-1-Ig, RRID:AB_2133396
- Product name
- KMO antibody
- Antibody type
- Monoclonal
- Description
- KMO antibody (Cat. #60029-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2D2F2
- Vial size
- 20ul, 150ul
Submitted references A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Quercetin inhibits gastric cancer cell proliferation and migration and is associated with the suppression of the IDO1-Kynurenine-AhR axis.
Ginsenoside compound K ameliorates depressive-like behaviors by targeting kynurenine 3-monooxygenase.
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Thrombin-induced kynurenine 3-monooxygenase causes variations in the kynurenine pathway, leading to neurological deficits in a murine intracerebral hemorrhage model.
Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine-3-monooxygenase with microglial decline.
Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.
Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity.
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.
Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas.
Yuan Q, Zhao Y, Zhou F, Zhang Y, Jia X, Yao J, Lv M, Wang J, Lv L
International journal of biological macromolecules 2026 May;361:151988
International journal of biological macromolecules 2026 May;361:151988
Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice.
Zhang Y, Gu K, Xin L, Xia Y, Yang G, Cai J, He Z, Qin LQ, Wan Z
NPJ science of food 2026 Mar 8;10(1)
NPJ science of food 2026 Mar 8;10(1)
Quercetin inhibits gastric cancer cell proliferation and migration and is associated with the suppression of the IDO1-Kynurenine-AhR axis.
Zhu M, Hu Q, Lu Y, Xu Q, Huang H, Chen K, Shuai X, Wang Y, Huang J, Guo Z
BMC cancer 2025 Nov 25;25(1):1916
BMC cancer 2025 Nov 25;25(1):1916
Ginsenoside compound K ameliorates depressive-like behaviors by targeting kynurenine 3-monooxygenase.
Li W, Kong Z, Yang L, Chen F, Chen Y, Han J, Sheng C, Zeng L, Hu Y, Zhao Y, Wang H, Bian Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157335
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157335
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Wang L, Ge S, Zhang Y, Feng D, Zhu T, Zhang L, Zhang C
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Thrombin-induced kynurenine 3-monooxygenase causes variations in the kynurenine pathway, leading to neurological deficits in a murine intracerebral hemorrhage model.
Ohnishi M, Banshoya K, Machida A, Kai T, Shimizu Y, Yano Y, Urabe Y, Tasaka S, Furutaguchi M, Shigemasa T, Akagi M, Maehara S, Hata T
Journal of pharmacological sciences 2025 Feb;157(2):65-74
Journal of pharmacological sciences 2025 Feb;157(2):65-74
Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine-3-monooxygenase with microglial decline.
Hasegawa M, Kunisawa K, Wulaer B, Kubota H, Kurahashi H, Sakata T, Ando H, Fujigaki S, Fujigaki H, Yamamoto Y, Nagai T, Saito K, Nabeshima T, Mouri A
British journal of pharmacology 2025 Apr;182(7):1466-1486
British journal of pharmacology 2025 Apr;182(7):1466-1486
Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.
Johnson EE, Southern WM, Doud B, Steiger B, Razzoli M, Bartolomucci A, Ervasti JM
Human molecular genetics 2024 Mar 20;33(7):594-611
Human molecular genetics 2024 Mar 20;33(7):594-611
Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity.
Morita N, Hoshi M, Hara T, Ninomiya S, Enoki T, Yoneda M, Tsurumi H, Saito K
Oncology letters 2021 Nov;22(5):790
Oncology letters 2021 Nov;22(5):790
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.
Korstanje R, Deutsch K, Bolanos-Palmieri P, Hanke N, Schroder P, Staggs L, Bräsen JH, Roberts IS, Sheehan S, Savage H, Haller H, Schiffer M
Journal of the American Society of Nephrology : JASN 2016 Nov;27(11):3271-3277
Journal of the American Society of Nephrology : JASN 2016 Nov;27(11):3271-3277
Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas.
Bosnyák E, Kamson DO, Guastella AR, Varadarajan K, Robinette NL, Kupsky WJ, Muzik O, Michelhaugh SK, Mittal S, Juhász C
Neuro-oncology 2015 Sep;17(9):1284-92
Neuro-oncology 2015 Sep;17(9):1284-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 60029-1-Ig(KMO antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Kynurenine 3 monooxygenase antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human Kynurenine 3 monooxygenase. This antibody recognizes human, mouse, rat antigen. The Kynurenine 3 monooxygenase antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 60029-1-Ig(KMO antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 60029-1-Ig(KMO antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
