HPA056942

antibody from Atlas Antibodies

Targeting: KMO

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA056942

Provider

Atlas Antibodies

Proper citation

Product name

Anti-KMO

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human KMO, Gene description: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), Validated applications: IHC, Uniprot ID: O15229, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.

Hornigold N, Dunn KR, Craven RA, Zougman A, Trainor S, Shreeve R, Brown J, Sewell H, Shires M, Knowles M, Fukuwatari T, Maher ER, Burns J, Bhattarai S, Menon M, Brazma A, Scelo G, Feulner L, Riazalhosseini Y, Lathrop M, Harris A, Selby PJ, Banks RE, Vasudev NS
British journal of cancer 2020 Jul;123(1):137-147

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human liver and testis tissues using HPA056942 antibody. Corresponding KMO RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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