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- Antigen structure
- References [17]
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- Product number
- 16253-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16253-1-AP, RRID:AB_2278140
- Product name
- EXO1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXO1 antibody (Cat. #16253-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay.
Phase separation of ERCC6L2-CtIP regulates the extent of DNA end resection.
The RING Finger E3 Ligase RNF25 Protects DNA Replication Forks Independently of its Canonical Roles in Ubiquitin Signaling.
The RING finger E3 ligase RNF25 protects DNA replication forks independently of its canonical roles in ubiquitin signaling.
HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.
BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL.
MRE11A: a novel negative regulator of human DNA mismatch repair.
EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks.
SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing.
HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation.
Telomeric Double Strand Breaks in G1 Human Cells Facilitate Formation of 5' C-Rich Overhangs and Recruitment of TERRA.
Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations.
DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
PCNA promotes processive DNA end resection by Exo1.
Hough SH, Jhujh SS, Awwad SW, Lewis OE, Lam S, Thomas JC, Mosler T, Bader A, Bartik L, McKee S, Amudhavalli S, Colin E, Damseh N, Clement E, Cacheiro P, Majumdar A, Smedley D, Fluss J, Giannini R, Thiffault I, Zagnoli Vieira G, Belotserkovskaya R, Smerdon SJ, Beli P, Galanty Y, Carnie CJ, Stewart GS, Jackson SP
EMBO molecular medicine 2026 Feb;18(2):492-513
EMBO molecular medicine 2026 Feb;18(2):492-513
Phase separation of ERCC6L2-CtIP regulates the extent of DNA end resection.
Yin Y, Lin J, Cai X, Nie R, Lin J, Li S, Xiang Z, Ling Y, Zhang Y, Zhou J, Chen J, Lin W, Duan J, Zheng X, Xie D, Cai M
Nature cell biology 2025 Oct;27(10):1771-1784
Nature cell biology 2025 Oct;27(10):1771-1784
The RING Finger E3 Ligase RNF25 Protects DNA Replication Forks Independently of its Canonical Roles in Ubiquitin Signaling.
Chiou LF, Jayaprakash D, Droby GN, Zhang X, Yang Y, Mills CA, Webb TS, Barker NK, Wu D, Herring LE, Bowser J, Vaziri C
bioRxiv : the preprint server for biology 2025 Jan 9;
bioRxiv : the preprint server for biology 2025 Jan 9;
The RING finger E3 ligase RNF25 protects DNA replication forks independently of its canonical roles in ubiquitin signaling.
Chiou LF, Droby GN, Jayaprakash D, Anand JR, Zhang X, Yang Y, Mills CA, Webb TS, Barker NK, Xie J, Wu D, Herring LE, Tomida J, Bowser JL, Vaziri C
Nature communications 2025 Aug 5;16(1):7214
Nature communications 2025 Aug 5;16(1):7214
HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.
He X, Li Y, Li J, Li Y, Chen S, Yan X, Xie Z, Du J, Chen G, Song J, Mei Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413121
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413121
BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL.
Gothwal SK, Refaat AM, Nakata M, Stanlie A, Honjo T, Begum NA
Nucleic acids research 2024 May 8;52(8):4422-4439
Nucleic acids research 2024 May 8;52(8):4422-4439
MRE11A: a novel negative regulator of human DNA mismatch repair.
Du D, Yang Y, Zhang Y, Wang G, Chen L, Guan X, Rasmussen LJ, Liu D
Cellular & molecular biology letters 2024 Mar 14;29(1):37
Cellular & molecular biology letters 2024 Mar 14;29(1):37
EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression.
Wang Z, Chao Z, Wang Q, Zou F, Song T, Xu L, Ning J, Cheng F
Journal of translational medicine 2024 Jan 26;22(1):104
Journal of translational medicine 2024 Jan 26;22(1):104
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks.
Zhao Y, Hou K, Li Y, Hao S, Liu Y, Na Y, Li C, Cui J, Xu X, Wu X, Wang H
Nucleic acids research 2023 Dec 11;51(22):12207-12223
Nucleic acids research 2023 Dec 11;51(22):12207-12223
SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing.
Liu W, Lu X, Zhao ZH, Su R, Li QL, Xue Y, Gao Z, Sun SS, Lei WL, Li L, An G, Liu H, Han Z, Ouyang YC, Hou Y, Wang ZB, Sun QY, Liu J
eLife 2022 Nov 10;11
eLife 2022 Nov 10;11
HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation.
Wu L, Shukla V, Yadavalli AD, Dinesh RK, Xu D, Rao A, Schatz DG
Genes & development 2022 Apr 1;36(7-8):433-450
Genes & development 2022 Apr 1;36(7-8):433-450
Telomeric Double Strand Breaks in G1 Human Cells Facilitate Formation of 5' C-Rich Overhangs and Recruitment of TERRA.
Nelson CB, Alturki TM, Luxton JJ, Taylor LE, Maranon DG, Muraki K, Murnane JP, Bailey SM
Frontiers in genetics 2021;12:644803
Frontiers in genetics 2021;12:644803
Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations.
Shen B, Chapman JH, Custance MF, Tricola GM, Jones CE, Furano AV
eLife 2020 Jan 6;9
eLife 2020 Jan 6;9
DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
Tammaro M, Liao S, Beeharry N, Yan H
Nucleic acids research 2016 Jan 8;44(1):221-31
Nucleic acids research 2016 Jan 8;44(1):221-31
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA
PLoS genetics 2015 Dec;11(12):e1005675
PLoS genetics 2015 Dec;11(12):e1005675
PCNA promotes processive DNA end resection by Exo1.
Chen X, Paudyal SC, Chin RI, You Z
Nucleic acids research 2013 Nov;41(20):9325-38
Nucleic acids research 2013 Nov;41(20):9325-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EXO1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EXO1. This antibody recognizes human antigen. The EXO1 antibody has been validated for the following applications: ELISA, WB analysis.
