27249-1-AP

antibody from Proteintech Group

Targeting: NF1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27249-1-AP

Provider

Proteintech Group

Product name

Neurofibromin 1 antibody

Antibody type

Polyclonal

Description

Neurofibromin 1 antibody (Cat. #27249-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Identification and validation of CARS1 p.E712V and NF1 p.Q2002X in sporadic Moyamoya disease across 30 trio pedigrees.

Wang Y, Zou Z, Chen G, Zhang Q, Li Y, Zhang Z, Tang X, Liu S, Zhuang T, Yu D, Duan L, Liu W
NPJ genomic medicine 2026 Jan 28;11(1):9

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Impact of Mutational Status on Intracellular Effects of Cell-Permeable CaaX Peptides in Pancreatic Cancer Cells.

Klußmann M, Matijass M, Neundorf I
Chembiochem : a European journal of chemical biology 2025 May 27;26(10):e202401076

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Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation.

Antón-Plágaro C, Chen KE, Guo Q, Liu M, Evans AJ, Lewis PA, Heesom KJ, Wilkinson KA, Collins BM, Cullen PJ
Nature communications 2025 Jul 30;16(1):6990

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Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma.

Pucci P, Lee LC, Han M, Matthews JD, Jahangiri L, Schlederer M, Manners E, Sorby-Adams A, Kaggie J, Trigg RM, Steel C, Hare L, James ER, Prokoph N, Ducray SP, Merkel O, Rifatbegovic F, Luo J, Taschner-Mandl S, Kenner L, Burke GAA, Turner SD
Nature communications 2024 Apr 23;15(1):3422

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IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.

Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q
Clinical and translational medicine 2023 Sep;13(9):e1427

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Survey of NF1 inactivation by surrogate immunohistochemistry in ovarian carcinomas.

Köbel M, Yang RZ, Kang EY, Al-Shamma Z, Cook LS, Kinloch M, Carey MS, Hopkins L, Nelson GS, McManus KJ, Vizeacoumar FS, Vizeacoumar FJ, Freywald A, Fu Y, Reuss DE, Lee CH
Gynecologic oncology 2023 Nov;178:80-88

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The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1.

Zhang L, Jiang L, Zeng L, Jin Z, Dong X, Zhang Y, Chen L, Shu Y, Liu Y, Huang Y
Journal of translational medicine 2023 May 5;21(1):306

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Characterization of Two Loss-of-Function NF1 Variants in Chinese Patients and Potential Molecular Interpretations of Phenotypes.

Zhang T, Han T, Dong Z, Li C, Lu W
Frontiers in genetics 2021;12:660592

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A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study.

Zhang T, Jia C, Dong Z, Li C, Lu W
Molecular genetics & genomic medicine 2021 May;9(5):e1643