Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 12714-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12714-1-AP, RRID:AB_2218388
- Product name
- ZNF238 antibody
- Antibody type
- Polyclonal
- Description
- ZNF238 antibody (Cat. #12714-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references p21/Zbtb18 repress the expression of cKit to regulate the self-renewal of hematopoietic stem cells.
Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
LINC02774 inhibits glycolysis in glioma to destabilize HIF-1α dependent on transcription factor RP58.
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.
ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis.
RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats.
Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.
Disease-associated missense variants in ZBTB18 disrupt DNA binding and impair the development of neurons within the embryonic cerebral cortex.
Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.
Rp58 and p27(kip1) coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.
The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development.
Wang N, Yang S, Li Y, Gou F, Lv Y, Zhao X, Wang Y, Xu C, Zhou B, Dong F, Ju Z, Cheng T, Cheng H
Protein & cell 2024 Nov 1;15(11):840-857
Protein & cell 2024 Nov 1;15(11):840-857
Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
Zhang L, Chen J, Yang X, Shen C, Huang J, Zhang D, Liu N, Liu C, Zhong Y, Chen Y, Tang K, Guo J, Cui T, Duan S, Li J, Huang S, Pan H, Zhang H, Tang X, Chang Y, Gao Y
Signal transduction and targeted therapy 2024 Jan 24;9(1):20
Signal transduction and targeted therapy 2024 Jan 24;9(1):20
LINC02774 inhibits glycolysis in glioma to destabilize HIF-1α dependent on transcription factor RP58.
Chen Y, Liu Y, Xiong J, Ouyang L, Tang M, Mao C, Li L, Xiao D, Liu S, Yang Z, Huang J, Tao Y
MedComm 2023 Oct;4(5):e364
MedComm 2023 Oct;4(5):e364
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.
Ferrarese R, Izzo A, Andrieux G, Lagies S, Bartmuss JP, Masilamani AP, Wasilenko A, Osti D, Faletti S, Schulzki R, Yuan S, Kling E, Ribecco V, Heiland DH, Tholen S, Prinz M, Pelicci G, Kammerer B, Boerries M, Carro MS
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis.
Wang R, Bhatt AB, Minden-Birkenmaier BA, Travis OK, Tiwari S, Jia H, Rosikiewicz W, Martinot O, Childs E, Loesch R, Tossou G, Jamieson S, Finkelstein D, Xu B, Labelle M
Science advances 2023 Jan 6;9(1):eabq3951
Science advances 2023 Jan 6;9(1):eabq3951
RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats.
Yang H, Zhang Z, Ding X, Jiang X, Tan L, Lin C, Xu L, Li G, Lu L, Qin Z, Feng X, Li M
Journal of pineal research 2023 Aug;75(1):e12885
Journal of pineal research 2023 Aug;75(1):e12885
Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.
Masilamani AP, Schulzki R, Yuan S, Haase IV, Kling E, Dewes F, Andrieux G, Börries M, Schnell O, Heiland DH, Schilling O, Ferrarese R, Carro MS
iScience 2022 Jul 15;25(7):104625
iScience 2022 Jul 15;25(7):104625
Disease-associated missense variants in ZBTB18 disrupt DNA binding and impair the development of neurons within the embryonic cerebral cortex.
Hemming IA, Clément O, Gladwyn-Ng IE, Cullen HD, Ng HL, See HB, Ngo L, Ulgiati D, Pfleger KDG, Agostino M, Heng JI
Human mutation 2019 Oct;40(10):1841-1855
Human mutation 2019 Oct;40(10):1841-1855
Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
Sagner A, Gaber ZB, Delile J, Kong JH, Rousso DL, Pearson CA, Weicksel SE, Melchionda M, Mousavy Gharavy SN, Briscoe J, Novitch BG
PLoS biology 2018 Feb;16(2):e2003127
PLoS biology 2018 Feb;16(2):e2003127
FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.
Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK
Neuron 2018 Dec 5;100(5):1083-1096.e5
Neuron 2018 Dec 5;100(5):1083-1096.e5
Rp58 and p27(kip1) coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.
Clément O, Hemming IA, Gladwyn-Ng IE, Qu Z, Li SS, Piper M, Heng JI
Neural development 2017 May 15;12(1):8
Neural development 2017 May 15;12(1):8
The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development.
Heng JI, Qu Z, Ohtaka-Maruyama C, Okado H, Kasai M, Castro D, Guillemot F, Tan SS
Cerebral cortex (New York, N.Y. : 1991) 2015 Mar;25(3):806-16
Cerebral cortex (New York, N.Y. : 1991) 2015 Mar;25(3):806-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12714-1-AP(ZNF238 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-ZNF238 (12714-1-AP for IP and Detection) with mouse cerebellum tissue.
- Sample type
- tissue