Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12011-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12011-1-AP, RRID:AB_2193981
- Product name
- SMYD3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SMYD3 antibody (Cat. #12011-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Macrophage-Derived Transcriptional Signatures Predict Prognosis and Drug Sensitivity in Thyroid Cancer: Integrative Analysis and Experimental Validation of SMYD3.
Integration of Methylation and Gene Expression Deciphered Candidate Biomarkers DAB2IP and SMYD3 in Delayed Encephalopathy After Carbon Monoxide Poisoning.
USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment.
SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.
SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins.
Effects of SMYD3 over-expression on cell cycle acceleration and cell proliferation in MDA-MB-231 human breast cancer cells.
Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma.
Xu S, Zhang X, Sun J, Qin M, Du H, Luo B
ImmunoTargets and therapy 2026;15:565624
ImmunoTargets and therapy 2026;15:565624
Integration of Methylation and Gene Expression Deciphered Candidate Biomarkers DAB2IP and SMYD3 in Delayed Encephalopathy After Carbon Monoxide Poisoning.
Yan H, Yuan D, Zhang Y, Luo H, Jiang P, Zhang Y, Wu Y, Hou L, Cheng Y, Yang F, Du Y, Zhu H, Zhao L, Li Y, Jiang Y, Gao Y
CNS neuroscience & therapeutics 2025 Feb;31(2):e70270
CNS neuroscience & therapeutics 2025 Feb;31(2):e70270
USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment.
Han S, Cui L, Wang B, Ruan Y, Shi M, Hong C, Guan X, Chen Z, Li Y, Liao Y, Ma M, Lu X, Wang H, Zhang Y, Liu C
Cancer immunology research 2025 Aug 1;13(8):1226-1245
Cancer immunology research 2025 Aug 1;13(8):1226-1245
SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.
Agborbesong E, Zhou JX, Zhang H, Li LX, Harris PC, Calvet JP, Li X
International journal of molecular sciences 2024 May 30;25(11)
International journal of molecular sciences 2024 May 30;25(11)
SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair.
Huang Y, Tang M, Hu Z, Cai B, Chen G, Jiang L, Xia Y, Guan P, Li X, Mao Z, Wan X, Lu W
Oncogenesis 2024 Jan 8;13(1):3
Oncogenesis 2024 Jan 8;13(1):3
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins.
Liu X, Wang J, Gao L, Liu H, Liu C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):185-199
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):185-199
Effects of SMYD3 over-expression on cell cycle acceleration and cell proliferation in MDA-MB-231 human breast cancer cells.
Ren TN, Wang JS, He YM, Xu CL, Wang SZ, Xi T
Medical oncology (Northwood, London, England) 2011 Dec;28 Suppl 1:S91-8
Medical oncology (Northwood, London, England) 2011 Dec;28 Suppl 1:S91-8
Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.
Lambrot R, Kimmins S
International journal of andrology 2011 Apr;34(2):110-23
International journal of andrology 2011 Apr;34(2):110-23
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma.
Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J
Carcinogenesis 2010 May;31(5):766-76
Carcinogenesis 2010 May;31(5):766-76
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12011-1-AP(SMYD3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-SMYD3 (IP:12011-1-AP, 4ug; Detection:12011-1-AP 1:500) with COLO 320 cells lysate 1280ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SMYD3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SMYD3. This antibody recognizes human,mouse,rat antigen. The SMYD3 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.