Antibody data
- Antibody Data
- Antigen structure
- References [36]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15146-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15146-1-AP, RRID:AB_2254244
- Product name
- S100 Beta antibody
- Antibody type
- Polyclonal
- Description
- S100 Beta antibody (Cat. #15146-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Supplemental N-3 Polyunsaturated Fatty Acids Limit A1-Specific Astrocyte Polarization via Attenuating Mitochondrial Dysfunction in Ischemic Stroke in Mice.
TSH Combined with TSHR Aggravates Diabetic Peripheral Neuropathy by Promoting Oxidative Stress and Apoptosis in Schwann Cells.
Systematic assessment of variability in the proteome of iPSC derivatives.
Mechanoreceptor synapses in the brainstem shape the central representation of touch.
Regulation of intestinal immunity and tissue repair by enteric glia.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Activation of UCP2 by anethole trithione suppresses neuroinflammation after intracerebral hemorrhage.
Neuron-Glia Interactions in Tuberous Sclerosis Complex Affect the Synaptic Balance in 2D and Organoid Cultures.
The Construction and Analysis of lncRNA-miRNA-mRNA Competing Endogenous RNA Network of Schwann Cells in Diabetic Peripheral Neuropathy.
Dentate Gyrus Proliferative Responses After Traumatic Brain Injury and Binge Alcohol in Adult Rats.
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
Establishment of a Jaw Fibrosarcoma Patient-Derived Xenograft and Evaluation of the Tumor Suppression Efficacy of Plumbagin Against Jaw Fibrosarcoma.
Exogenous neuritin treatment improves survivability and functions of Schwann cells with improved outgrowth of neurons in rat diabetic neuropathy.
Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model.
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
A recessive Trim2 mutation causes an axonal neuropathy in mice.
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice.
Transforming Growth Factor Beta 1 Regulates Fibroblast Growth Factor 7 Expression in Schwann Cells.
Ellagic acid supports neuron by regulating astroglia Nrf2.
Astrocyte Subtype Vulnerability in Stem Cell Models of Vanishing White Matter.
Oleoylethanolamide inhibits glial activation via moudulating PPARα and promotes motor function recovery after brain ischemia.
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
HIF-1α mediates tumor-nerve interactions through the up-regulation of GM-CSF in pancreatic ductal adenocarcinoma.
Fabrication of high-strength mecobalamin loaded aligned silk fibroin scaffolds for guiding neuronal orientation.
Dynamic Expression and New Functions of Early B Cell Factor 2 in Cerebellar Development.
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
miR-1b overexpression suppressed proliferation and migration of RSC96 and increased cell apoptosis.
Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment.
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Transient receptor potential vanilloid 1-immunoreactive signals in murine enteric glial cells.
Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors.
NDRG2 as a marker protein for brain astrocytes.
Tetrandrine ameliorates cognitive impairment via inhibiting astrocyte-derived S100B activation in a rat model of chronic cerebral hypoperfusion.
Cao J, Dong L, Luo J, Zeng F, Hong Z, Liu Y, Zhao Y, Xia Z, Zuo D, Xu L, Tao T
Oxidative medicine and cellular longevity 2021;2021:5524705
Oxidative medicine and cellular longevity 2021;2021:5524705
TSH Combined with TSHR Aggravates Diabetic Peripheral Neuropathy by Promoting Oxidative Stress and Apoptosis in Schwann Cells.
Fan J, Pan Q, Gao Q, Li W, Xiao F, Guo L
Oxidative medicine and cellular longevity 2021;2021:2482453
Oxidative medicine and cellular longevity 2021;2021:2482453
Systematic assessment of variability in the proteome of iPSC derivatives.
Beekhuis-Hoekstra SD, Watanabe K, Werme J, de Leeuw CA, Paliukhovich I, Li KW, Koopmans F, Smit AB, Posthuma D, Heine VM
Stem cell research 2021 Oct;56:102512
Stem cell research 2021 Oct;56:102512
Mechanoreceptor synapses in the brainstem shape the central representation of touch.
Lehnert BP, Santiago C, Huey EL, Emanuel AJ, Renauld S, Africawala N, Alkislar I, Zheng Y, Bai L, Koutsioumpa C, Hong JT, Magee AR, Harvey CD, Ginty DD
Cell 2021 Oct 28;184(22):5608-5621.e18
Cell 2021 Oct 28;184(22):5608-5621.e18
Regulation of intestinal immunity and tissue repair by enteric glia.
Progatzky F, Shapiro M, Chng SH, Garcia-Cassani B, Classon CH, Sevgi S, Laddach A, Bon-Frauches AC, Lasrado R, Rahim M, Amaniti EM, Boeing S, Shah K, Entwistle LJ, Suárez-Bonnet A, Wilson MS, Stockinger B, Pachnis V
Nature 2021 Nov;599(7883):125-130
Nature 2021 Nov;599(7883):125-130
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
Activation of UCP2 by anethole trithione suppresses neuroinflammation after intracerebral hemorrhage.
Yan XL, Xu FY, Ji JJ, Song P, Pei YQ, He MJ, Wang ZC, You SJ, Hua ZC, Cheng J, Jia J
Acta pharmacologica Sinica 2021 Jun 28;
Acta pharmacologica Sinica 2021 Jun 28;
Neuron-Glia Interactions in Tuberous Sclerosis Complex Affect the Synaptic Balance in 2D and Organoid Cultures.
Dooves S, van Velthoven AJH, Suciati LG, Heine VM
Cells 2021 Jan 12;10(1)
Cells 2021 Jan 12;10(1)
The Construction and Analysis of lncRNA-miRNA-mRNA Competing Endogenous RNA Network of Schwann Cells in Diabetic Peripheral Neuropathy.
Wang C, Xu X, Chen J, Kang Y, Guo J, Duscher D, Yang X, Guo G, Ren S, Xiong H, Yuan M, Jiang T, Machens HG, Chen Z, Chen Y
Frontiers in bioengineering and biotechnology 2020;8:490
Frontiers in bioengineering and biotechnology 2020;8:490
Dentate Gyrus Proliferative Responses After Traumatic Brain Injury and Binge Alcohol in Adult Rats.
Ton ST, Adamczyk NS, Gerling JP, Vaagenes IC, Wu JY, Hsu K, O'Brien TE, Tsai SY, Kartje GL
Neuroscience insights 2020;15:2633105520968904
Neuroscience insights 2020;15:2633105520968904
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
He M, Qian K, Zhang Y, Huang XF, Deng C, Zhang B, Gao G, Li J, Xie H, Sun T
Frontiers in neuroscience 2020;14:589650
Frontiers in neuroscience 2020;14:589650
Establishment of a Jaw Fibrosarcoma Patient-Derived Xenograft and Evaluation of the Tumor Suppression Efficacy of Plumbagin Against Jaw Fibrosarcoma.
Xin Y, Li S, Jiang Q, Hu F, He Y, Zhang J
Frontiers in oncology 2020;10:1479
Frontiers in oncology 2020;10:1479
Exogenous neuritin treatment improves survivability and functions of Schwann cells with improved outgrowth of neurons in rat diabetic neuropathy.
Xi C, Zhang Y, Yan M, Lv Q, Lu H, Zhou J, Wang Y, Li J
Journal of cellular and molecular medicine 2020 Sep;24(17):10166-10176
Journal of cellular and molecular medicine 2020 Sep;24(17):10166-10176
Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model.
Bose D, Saha P, Mondal A, Fanelli B, Seth RK, Janulewicz P, Sullivan K, Lasley S, Horner R, Colwell RR, Shetty AK, Klimas N, Chatterjee S
Nutrients 2020 Sep 10;12(9)
Nutrients 2020 Sep 10;12(9)
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD
Nature 2020 Jun;582(7813):550-556
Nature 2020 Jun;582(7813):550-556
A recessive Trim2 mutation causes an axonal neuropathy in mice.
Li JJ, Sarute N, Lancaster E, Otkiran-Clare G, Fagla BM, Ross SR, Scherer SS
Neurobiology of disease 2020 Jul;140:104845
Neurobiology of disease 2020 Jul;140:104845
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
Li P, Li Y, Dai Y, Wang B, Li L, Jiang B, Wu P, Xu J
Cytokine 2020 Jul;131:155106
Cytokine 2020 Jul;131:155106
Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice.
Zou W, Lv Y, Liu ZI, Xia P, Li H, Jiao J
Scientific reports 2020 Jul 24;10(1):12435
Scientific reports 2020 Jul 24;10(1):12435
Transforming Growth Factor Beta 1 Regulates Fibroblast Growth Factor 7 Expression in Schwann Cells.
Nguyen D, Sulaiman OAR
The Ochsner journal 2019 Spring;19(1):7-12
The Ochsner journal 2019 Spring;19(1):7-12
Ellagic acid supports neuron by regulating astroglia Nrf2.
Wang GQ, He XM, Zhu GF, Li DD, Shi JS, Zhang F
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Astrocyte Subtype Vulnerability in Stem Cell Models of Vanishing White Matter.
Leferink PS, Dooves S, Hillen AEJ, Watanabe K, Jacobs G, Gasparotto L, Cornelissen-Steijger P, van der Knaap MS, Heine VM
Annals of neurology 2019 Nov;86(5):780-792
Annals of neurology 2019 Nov;86(5):780-792
Oleoylethanolamide inhibits glial activation via moudulating PPARα and promotes motor function recovery after brain ischemia.
Luo D, Zhang Y, Yuan X, Pan Y, Yang L, Zhao Y, Zhuo R, Chen C, Peng L, Li W, Jin X, Zhou Y
Pharmacological research 2019 Mar;141:530-540
Pharmacological research 2019 Mar;141:530-540
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB
Cell stem cell 2019 Mar 7;24(3):363-375.e9
Cell stem cell 2019 Mar 7;24(3):363-375.e9
HIF-1α mediates tumor-nerve interactions through the up-regulation of GM-CSF in pancreatic ductal adenocarcinoma.
Wang H, Jia R, Zhao T, Li X, Lang M, Lan C, Wang H, Li Z, Zhou B, Wu L, Sun Y, Wang X, Ren H, Hao J
Cancer letters 2019 Jul 1;453:10-20
Cancer letters 2019 Jul 1;453:10-20
Fabrication of high-strength mecobalamin loaded aligned silk fibroin scaffolds for guiding neuronal orientation.
Zhang L, Xu L, Li G, Yang Y
Colloids and surfaces. B, Biointerfaces 2019 Jan 1;173:689-697
Colloids and surfaces. B, Biointerfaces 2019 Jan 1;173:689-697
Dynamic Expression and New Functions of Early B Cell Factor 2 in Cerebellar Development.
Badaloni A, Casoni F, Croci L, Chiara F, Bizzoca A, Gennarini G, Cremona O, Hawkes R, Consalez GG
Cerebellum (London, England) 2019 Dec;18(6):999-1010
Cerebellum (London, England) 2019 Dec;18(6):999-1010
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor.
Su L, Xia W, Shen T, Liang Q, Wang W, Li H, Jiao J
Nucleic acids research 2018 Sep 28;46(17):8817-8831
Nucleic acids research 2018 Sep 28;46(17):8817-8831
The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial.
Zhao Z, Lu C, Li T, Wang W, Ye W, Zeng R, Ni L, Lai Z, Wang X, Liu C
Journal of pineal research 2018 Nov;65(4):e12521
Journal of pineal research 2018 Nov;65(4):e12521
miR-1b overexpression suppressed proliferation and migration of RSC96 and increased cell apoptosis.
Liu YP, Xu P, Guo CX, Luo ZR, Zhu J, Mou FF, Cai H, Wang C, Ye XC, Shao SJ, Guo HD
Neuroscience letters 2018 Nov 20;687:137-145
Neuroscience letters 2018 Nov 20;687:137-145
Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment.
Dooves S, Bugiani M, Wisse LE, Abbink TEM, van der Knaap MS, Heine VM
Neuropathology and applied neurobiology 2018 Jun;44(4):391-403
Neuropathology and applied neurobiology 2018 Jun;44(4):391-403
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Shepard MJ, Padmanaban V, Edwards NA, Chittiboina P, Ray-Chaudhury A, Heiss JD
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
Transient receptor potential vanilloid 1-immunoreactive signals in murine enteric glial cells.
Yamamoto M, Nishiyama M, Iizuka S, Suzuki S, Suzuki N, Aiso S, Nakahara J
World journal of gastroenterology 2016 Nov 28;22(44):9752-9764
World journal of gastroenterology 2016 Nov 28;22(44):9752-9764
Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors.
Edri R, Yaffe Y, Ziller MJ, Mutukula N, Volkman R, David E, Jacob-Hirsch J, Malcov H, Levy C, Rechavi G, Gat-Viks I, Meissner A, Elkabetz Y
Nature communications 2015 Mar 23;6:6500
Nature communications 2015 Mar 23;6:6500
NDRG2 as a marker protein for brain astrocytes.
Flügge G, Araya-Callis C, Garea-Rodriguez E, Stadelmann-Nessler C, Fuchs E
Cell and tissue research 2014 Jul;357(1):31-41
Cell and tissue research 2014 Jul;357(1):31-41
Tetrandrine ameliorates cognitive impairment via inhibiting astrocyte-derived S100B activation in a rat model of chronic cerebral hypoperfusion.
Chen L, Chen L, Lv Y, Cui Z, Bei G, Qin G, Zhou J, Ge T
Neurological research 2013 Jul;35(6):614-21
Neurological research 2013 Jul;35(6):614-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 15146-1-AP(S100B antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin cancer using 15146-1-AP(S100B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The S100B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human S100B. This antibody recognizes human,mouse,rat antigen. The S100B antibody has been validated for the following applications: ELISA, WB, IHC analysis.