Antibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Western blot [1]
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- Product number
- BS6002 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- S100B polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human S100B.
- Description
- S-100 Ï« and ÉÇ, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin Ï« and parvalbumin ÉÇ (also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 Ï« chain and S-100 ÉÇ chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two Ï« chains, two ÉÇ chains or one Ï« and one ÉÇ chain. S-100 localizes to the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of S100B pAb in extracts from A375 cells.