Antibody data
- Antibody Data
- Antigen structure
- References [36]
- Comments [0]
- Validations [0]
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- Product number
- 66616-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- S100 Beta antibody
- Antibody type
- Monoclonal
- Description
- S100 Beta antibody (Cat. #66616-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, pig, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G10F4
- Vial size
- 20ul, 150ul
Submitted references NR4A3 alleviates diabetic neuropathy via GLS2-mediated mitochondrial repair and Schwann cell differentiation.
S100B induces angiogenesis via the clathrin/FOXO1/β-catenin signaling pathway and contributes to Bevacizumab resistance in epithelial ovarian cancer.
Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC-Derived Cortical Organoids.
Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium.
M2 polarization of macrophage induced by IL-33 promotes mouse sciatic nerve regeneration.
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury.
Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling.
Cerebrospinal fluid-contacting neurons: a promising source for adult neural stem cell transplantation in spinal cord injury treatment.
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes.
Hippocampus carbonic anhydrase 1 via ERK pathway may be involved in depressive like behaviors.
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Astrocytic modulation of GABA transmission in the VTA limits progression of anxiety- and depression-like behaviors in adult mice.
Glutamine synthetase in astrocytes of the caudate and putamen is responsible for locomotor sensitization after nicotine exposure.
Sonic hedgehog promotes Schwann cell proliferation through PI3K/AKT/cyclin E1 pathway.
Impact of O-GlcNAcylation Elevation on Mitophagy and Glia in the Dentate Gyrus.
Ventricular-subventricular zone stem cell niche adaptations in a mouse model of post-infectious hydrocephalus.
Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport.
Impact of O -GlcNAcylation elevation on mitophagy and glia in the dentate gyrus.
Knockdown of Tlr3 in dorsal striatum reduces ethanol consumption and acute functional tolerance in male mice.
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life.
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice.
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
GAP-43 targeted indocyanine green-loaded near-infrared fluorescent probe for real-time mapping of perineural invasion lesions in pancreatic cancer in vivo.
Motor neurons transplantation alleviates neurofibrogenesis during chronic degeneration by reversibly regulating Schwann cells epithelial-mesenchymal transition.
Platelet-Rich Plasma Gel-Loaded Collagen/Chitosan Composite Film Accelerated Rat Sciatic Nerve Injury Repair.
α-Synuclein induces prodromal symptoms of Parkinson's disease via activating TLR2/MyD88/NF-κB pathway in Schwann cells of vagus nerve in a rat model.
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson's-like pathology burden.
Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.
High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma.
Nogo-C Inhibits Peripheral Nerve Regeneration by Regulating Schwann Cell Apoptosis and Dedifferentiation.
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway.
Pang B, Chen S, Bai Y, Zhang Y, Wang Z
iScience 2026 May 15;29(5):115515
iScience 2026 May 15;29(5):115515
S100B induces angiogenesis via the clathrin/FOXO1/β-catenin signaling pathway and contributes to Bevacizumab resistance in epithelial ovarian cancer.
Xu H, Li W, Yue H, Bai Y, Li J, Lu X, Wang J
Journal of advanced research 2026 Mar;81:613-636
Journal of advanced research 2026 Mar;81:613-636
Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC-Derived Cortical Organoids.
Labra SR, Compher J, Prabhavalkar A, Almaraz M, Cedeño Kwong C, Baal C, Talantova M, Dolatabadi N, Piña-Sanz J, Wang Y, Yoon L, Ghatak S, Gao Z, Zhang Y, Trudler D, Massey L, Lin W, Balistreri A, Bula M, Schork NJ, Mondala TS, Head SR, Kelly JW, Lipton SA
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(17):e14783
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(17):e14783
Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium.
Jia W, Yan H, Huang J, Liu W, Fu Z, Tian D, Xu W, Chen X, Gao Y, Yu H
Stem cell research & therapy 2026 Mar 11;17(1)
Stem cell research & therapy 2026 Mar 11;17(1)
M2 polarization of macrophage induced by IL-33 promotes mouse sciatic nerve regeneration.
Xu D, Li Y, Zhang Q, Wu W, Du Y, Liu J, Shen J, Jin X, Li X, Guo J, Li L, Wen J
Cell & bioscience 2026 Feb 8;16(1)
Cell & bioscience 2026 Feb 8;16(1)
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
Qi T, Wang X, Wu L, Han M, Zhou C, Wu B, Pei X, He C
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury.
Shi G, Hao X, Tu JF, Chen W, Fu Y, Ma X, Liu C, Li H
Journal of pain research 2025;18:663-671
Journal of pain research 2025;18:663-671
Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling.
Ding K, Liu X, Zeng B, Liu S, Zhang L, Li B, Zhou J, Su X, Wang J
Frontiers in immunology 2025;16:1552993
Frontiers in immunology 2025;16:1552993
Cerebrospinal fluid-contacting neurons: a promising source for adult neural stem cell transplantation in spinal cord injury treatment.
Luo Z, Shangguan Z, Cao L, Zhang Y, Li Q, Shi X, Fu J, Wang C, Dou X, Tan W, Li Q
Frontiers in cell and developmental biology 2025;13:1549194
Frontiers in cell and developmental biology 2025;13:1549194
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Wang Y, Zhou Y, Liu J, Liu C, Li Z, Sun X
Neurochemistry international 2025 May;185:105940
Neurochemistry international 2025 May;185:105940
Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes.
Bhupana JN, Pabon A, Leung HH, Rajmohamed MA, Kim SH, Tong Y, Jang MH, Wong CO
Nature communications 2025 May 31;16(1):5073
Nature communications 2025 May 31;16(1):5073
Hippocampus carbonic anhydrase 1 via ERK pathway may be involved in depressive like behaviors.
Cheng K, Chen C, Deng S, Xu F, Chen X, Yang J, Wang G, Xie P
Journal of affective disorders 2025 Mar 15;373:186-195
Journal of affective disorders 2025 Mar 15;373:186-195
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Chi D, Zhang K, Zhang J, He Z, Zhou H, Huang W, Liu Y, Huang J, Zeng W, Bai X, Ou C, Ouyang H
Nature communications 2025 Mar 14;16(1):2528
Nature communications 2025 Mar 14;16(1):2528
Astrocytic modulation of GABA transmission in the VTA limits progression of anxiety- and depression-like behaviors in adult mice.
Du J, Diao H, Xu Y, Li X, Yuan C, Nie L, Zhang H, Li J, Wang Y
Cell reports 2025 Jun 24;44(6):115824
Cell reports 2025 Jun 24;44(6):115824
Glutamine synthetase in astrocytes of the caudate and putamen is responsible for locomotor sensitization after nicotine exposure.
Yang JH, Sohn S, Kim S, Kim J, Seo SY, Kazmi A, Woo H, Wang JQ, Choe ES
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6399-6414
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6399-6414
Sonic hedgehog promotes Schwann cell proliferation through PI3K/AKT/cyclin E1 pathway.
Zhang Q, Du Y, Xu D, Zhang H, Li Y, Li L, Liu J, Jin X, Guo J, Wen J
Tissue & cell 2025 Aug;95:102858
Tissue & cell 2025 Aug;95:102858
Impact of O-GlcNAcylation Elevation on Mitophagy and Glia in the Dentate Gyrus.
Kramer J, Fu S, Ouyang X, Rohwer E, Chatham JC, Young ME, Darley-Usmar V, Zhang J
Journal of neurochemistry 2025 Aug;169(8):e70205
Journal of neurochemistry 2025 Aug;169(8):e70205
Ventricular-subventricular zone stem cell niche adaptations in a mouse model of post-infectious hydrocephalus.
Herman J, Rittenhouse N, Mandino F, Majid M, Wang Y, Mezger A, Kump A, Kadian S, Lake EMR, Verardi PH, Conover JC
Frontiers in neuroscience 2024;18:1429829
Frontiers in neuroscience 2024;18:1429829
Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport.
Bai H, Zhang S, Yang H, Wang J, Chen H, Li J, Li L, Yang Q, Peng B, Zhu Z, Ni S, Liu K, Lei W, Tao TH, Feng Y
Bioactive materials 2024 Sep;39:287-301
Bioactive materials 2024 Sep;39:287-301
Impact of O -GlcNAcylation elevation on mitophagy and glia in the dentate gyrus.
Kramer J, Chatham JC, Young ME, Darley-Usmar V, Zhang J
bioRxiv : the preprint server for biology 2024 Sep 20;
bioRxiv : the preprint server for biology 2024 Sep 20;
Knockdown of Tlr3 in dorsal striatum reduces ethanol consumption and acute functional tolerance in male mice.
Dilly GA, Blednov YA, Warden AS, Ezerskiy L, Fleischer C, Plotkin JD, Patil S, Osterndorff-Kahanek EA, Mayfield J, Mayfield RD, Homanics GE, Messing RO
Brain, behavior, and immunity 2024 May;118:437-448
Brain, behavior, and immunity 2024 May;118:437-448
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life.
Holota R, Dečmanová V, Alexovič Matiašová A, Košuth J, Slovinská L, Pačut L, Tomori Z, Daxnerová Z, Ševc J
Histochemistry and cell biology 2024 Mar;161(3):269-286
Histochemistry and cell biology 2024 Mar;161(3):269-286
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Guo H, Li Y, Wang S, Yang Y, Xu T, Zhao J, Wang J, Zuo W, Wang P, Zhao G, Wang H, Hou W, Dong H, Cai Y
Redox biology 2024 Aug;74:103234
Redox biology 2024 Aug;74:103234
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice.
Chen Y, Shang T, Sun J, Ji Y, Gong L, Li A, Ding F, Shen M, Zhang Q
The European journal of neuroscience 2024 Aug;60(4):4503-4517
The European journal of neuroscience 2024 Aug;60(4):4503-4517
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
Xu B, Zhou Z, Fang J, Wang J, Tao K, Liu J, Liu S
Free radical biology & medicine 2023 Nov 1;208:319-333
Free radical biology & medicine 2023 Nov 1;208:319-333
GAP-43 targeted indocyanine green-loaded near-infrared fluorescent probe for real-time mapping of perineural invasion lesions in pancreatic cancer in vivo.
Lu WL, Kuang H, Gu J, Hu X, Chen B, Fan Y
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102671
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102671
Motor neurons transplantation alleviates neurofibrogenesis during chronic degeneration by reversibly regulating Schwann cells epithelial-mesenchymal transition.
Wu Z, Ding H, Chen Y, Huang C, Chen X, Hu H, Chen Y, Zhang W, Fang X
Experimental neurology 2023 Jan;359:114272
Experimental neurology 2023 Jan;359:114272
Platelet-Rich Plasma Gel-Loaded Collagen/Chitosan Composite Film Accelerated Rat Sciatic Nerve Injury Repair.
Yuan B, Zheng X, Wu ML, Yang Y, Chen JW, Gao HC, Liu J
ACS omega 2023 Jan 24;8(3):2931-2941
ACS omega 2023 Jan 24;8(3):2931-2941
α-Synuclein induces prodromal symptoms of Parkinson's disease via activating TLR2/MyD88/NF-κB pathway in Schwann cells of vagus nerve in a rat model.
Cheng Y, Tong Q, Yuan Y, Song X, Jiang W, Wang Y, Li W, Li Y, Zhang K
Journal of neuroinflammation 2023 Feb 14;20(1):36
Journal of neuroinflammation 2023 Feb 14;20(1):36
Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway.
Hu B, Zhang H, Xu M, Li L, Wu M, Zhang S, Liu X, Xia W, Xu K, Xiao J, Zhang H, Ni L
Frontiers in pharmacology 2022;13:778680
Frontiers in pharmacology 2022;13:778680
Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson's-like pathology burden.
Delic V, Karp JH, Guzman M, Arismendi GR, Stalnaker KJ, Burton JA, Murray KE, Stamos JP, Beck KD, Sokratian A, West AB, Citron BA
Acta neuropathologica communications 2022 Nov 26;10(1):170
Acta neuropathologica communications 2022 Nov 26;10(1):170
Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.
Li P, Song R, Du Y, Liu H, Li X
Cellular and molecular life sciences : CMLS 2022 Jul 8;79(8):407
Cellular and molecular life sciences : CMLS 2022 Jul 8;79(8):407
High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma.
Wang Z, Chen H, Xue L, He W, Shu W, Wu H, Wang Z
Translational oncology 2021 Aug;14(8):101146
Translational oncology 2021 Aug;14(8):101146
Nogo-C Inhibits Peripheral Nerve Regeneration by Regulating Schwann Cell Apoptosis and Dedifferentiation.
Jia B, Huang W, Wang Y, Zhang P, Wang Z, Zheng M, Wang T
Frontiers in neuroscience 2020;14:616258
Frontiers in neuroscience 2020;14:616258
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Xiaoying L, Li T, Yu S, Jiusheng J, Jilin Z, Jiayi W, Dongxin L, Wengang F, Xinyue Z, Hao Y, Yuhua C, Deshu S
Neurochemical research 2019 Apr;44(4):905-916
Neurochemical research 2019 Apr;44(4):905-916
Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway.
Wang J, Zhou F, Wang D, Li J, Lu D, Li Q, Zhou H, Li W, Wang Q, Wu Y, Xie J, Wen T
Experimental neurology 2018 Apr;302:214-229
Experimental neurology 2018 Apr;302:214-229
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