27676-1-AP

antibody from Proteintech Group

Targeting: GRIN1 GluN1, NMDAR1

Provider product page for 27676-1-AP

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
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Product number: 27676-1-AP - Provider product page
Provider: Proteintech Group
Product name: GRIN1 antibody
Antibody type: Polyclonal
Description: GRIN1 antibody (Cat. #27676-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

GRIN1 protein structure - 27676-1-AP shown in red.

Submitted references The dynamic impairment of synaptic transmission in the PCx-IL engram circuit contributes to early olfactory memory decline in Alzheimer's disease.

Yan Y, Song D, Li G, Li J, Tang Y, Li D, Mao J, Li H, Liu X, Yu D, Ma F, Pang Y, Jin Y, Deng Y, Qiu Y, Quan Z, Ni J, Cheng Y, Wang Z, Dong Z, Hong Q
Molecular psychiatry 2026 Mar 25;

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Wang RF, Yuan PP, Chen L, Zhang ZK, Zhang BX, Chen L, Yuan SM, Zhao YF, Zhou N, Zheng XK, Feng WS
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Cu(OH)(2) nanopesticide induced adolescent social behavior deficits via long noncoding RNA-mediated synaptic network dysfunction.

Ren Z, Duan Y, Ren M, Cai Y, Liang J, Wang X, Sun J, Ren D, Ku T, Ning X, Sang N
Journal of hazardous materials 2026 Feb 15;504:141294

IRF7 in peripheral monocytes drives BBB disruption in anti-NMDAR encephalitis.

Li Q, Xiao L, Li J, Huang Y, Shen S, Li H, Peng F, He H, Huang S, Sun J, Qiu W, Cai W, Shu Y
Brain, behavior, and immunity 2025 Oct;129:960-974

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.

Wang W, Wang Y, Huang X, Wu P, Li L, Zhang Y, Chen Y, Chen Z, Li C, Zhou Y, Zhang J
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Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice.

Wang J, Zhang J, Li J, Gao Q, Chen J, Jia C, Gu X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Feb 26;45(9)

Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.

Guo H, Zhang H, Zhang C, Shen Y, Jiang L, Yang M, Zhang Y, Zhang N, Zhang R, Yu R, Yang Y, Tian X
JCI insight 2025 Aug 22;10(16)

Reactive microglia partially envelop viable neurons in prion diseases.

Makarava N, Safadi T, Bocharova O, Mychko O, Pandit NP, Molesworth K, Baiardi S, Zhang L, Parchi P, Baskakov IV
The Journal of clinical investigation 2024 Oct 3;134(23)

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Li Y, Yang Y, Guan X, Liu Z, Pan L, Wang Y, Jia X, Yang J, Hou T
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Li J, Yao D, Zhang T, Tong T, Shen J, Yan S, Zeng J, Aslam MS, Li M, You Z, Li J, Li Z, Li Y, Hao C, Meng X
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DPP-4 inhibition by linagliptin ameliorates age-related mild cognitive impairment by regulating microglia polarization in mice.

Zhuge F, Zheng L, Pan Y, Ni L, Fu Z, Shi J, Ni Y
Experimental neurology 2024 Mar;373:114689

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Ban Y, Yang X, Tan D, Gong C, Gao Y, Yuan J, Chen Y, Wang Y, Xu T
Neurochemistry international 2024 Jun;176:105727

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Yang C, Huang YT, Yao YF, Fu JY, Long YS
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A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling.

Wu Z, Yin Y, Liu R, Li X, Sun Y, Yau SY, Wu L, Liu Y, Adzic M, Zhang H, Chen G
Journal of ethnopharmacology 2024 Dec 5;335:118647

Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.

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Cell discovery 2024 Aug 20;10(1):87

Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.

Jiang C, Wang C, Qu W, Wang Y, Wang H, Wei X, Wang M, He Q, Wang Y, Yuan L, Gao Y
Heliyon 2023 Nov;9(11):e21743

Glutamate ionotropic receptor NMDA type subunit 1: A novel potential protein target of dapagliflozin against renal interstitial fibrosis.

Liu Y, Wang Y, Chen S, Bai L, Li F, Wu Y, Zhang L, Wang X
European journal of pharmacology 2023 Mar 15;943:175556

Identification of a robust scoring system based on metabolic genes followed by in-depth validation of ATP1A3 in glioma.

Ji Q, Tu Z, Liu J, Huang K, Zhu X, Li J
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Science advances 2022 Sep 30;8(39):eabq4736

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Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.

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